Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 2
1993 4
1995 2
1996 1
1997 1
1998 1
2001 3
2004 1
2007 1
2008 6
2009 3
2010 6
2011 3
2012 4
2013 6
2014 8
2015 2
2016 11
2017 10
2018 9
2019 12
2020 11
2021 8
2022 7
2023 8
2024 6

Text availability

Article attribute

Article type

Publication date

Search Results

123 results

Results by year

Filters applied: . Clear all
Page 1
African Swine Fever Virus Envelope Glycoprotein CD2v Interacts with Host CSF2RA to Regulate the JAK2-STAT3 Pathway and Inhibit Apoptosis to Facilitate Virus Replication.
Gao Q, Yang Y, Luo Y, Chen X, Gong T, Wu D, Feng Y, Zheng X, Wang H, Zhang G, Lu G, Gong L. Gao Q, et al. J Virol. 2023 Apr 27;97(4):e0188922. doi: 10.1128/jvi.01889-22. Epub 2023 Apr 6. J Virol. 2023. PMID: 37022174 Free PMC article.
In this study, CSF2RA small interfering RNA (siRNA) downregulated the JAK2-STAT3 pathway and promoted apoptosis to inhibit ASFV replication. Taken together, ASFV replication requires the JAK2-STAT3 pathway, while CD2v interacts with CSF2RA to regulate the JAK2-STAT3 …
In this study, CSF2RA small interfering RNA (siRNA) downregulated the JAK2-STAT3 pathway and promoted apoptosis to inhibit ASFV repli …
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome.
Sun J, Zhao J, Jiang F, Wang L, Xiao Q, Han F, Chen J, Yuan S, Wei J, Larsson SC, Zhang H, Dunlop MG, Farrington SM, Ding K, Theodoratou E, Li X. Sun J, et al. Genome Med. 2023 Sep 19;15(1):75. doi: 10.1186/s13073-023-01229-9. Genome Med. 2023. PMID: 37726845 Free PMC article.
Elevated levels of two proteins (GREM1, CHRDL2) and decreased levels of 11 proteins were associated with an increased risk of CRC, among which four (GREM1, CLSTN3, CSF2RA, CD86) were prioritized with the most convincing evidence. ...Two interactive pairs of proteins (GREM1 …
Elevated levels of two proteins (GREM1, CHRDL2) and decreased levels of 11 proteins were associated with an increased risk of CRC, among whi …
Pulmonary alveolar proteinosis.
Trapnell BC, Nakata K, Bonella F, Campo I, Griese M, Hamilton J, Wang T, Morgan C, Cottin V, McCarthy C. Trapnell BC, et al. Nat Rev Dis Primers. 2019 Mar 7;5(1):16. doi: 10.1038/s41572-019-0066-3. Nat Rev Dis Primers. 2019. PMID: 30846703 Review.
PAP can be classified into different types on the basis of the pathogenetic mechanism: primary PAP is characterized by the disruption of granulocyte-macrophage colony-stimulating factor (GM-CSF) signalling and can be autoimmune (caused by elevated levels of GM-CSF autoantibodies) …
PAP can be classified into different types on the basis of the pathogenetic mechanism: primary PAP is characterized by the disruption of gra …
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
Zong F, Li S, Wang Y, Xiao N, Deng M, Zhang Z, Su D, Gao B, Zhou D, Hu L, Yang H. Zong F, et al. Front Immunol. 2022 Sep 20;13:900755. doi: 10.3389/fimmu.2022.900755. eCollection 2022. Front Immunol. 2022. PMID: 36203597 Free PMC article.
Survival was greater in Csf2ra KO mice 21 days after RT inhalation compared with WT mice. Highly co-expressed genes that probably attenuated the pro-inflammatory response in the lung of Csf2ra KO mice were identified. Bioinformatics analysis revealed that transcript …
Survival was greater in Csf2ra KO mice 21 days after RT inhalation compared with WT mice. Highly co-expressed genes that probably att …
miR-532-3p-CSF2RA Axis as a Key Regulator of Vulnerable Atherosclerotic Plaque Formation.
Huang R, Cao Y, Li H, Hu Z, Zhang H, Zhang L, Su W, Xu Y, Liang L, Melgiri ND, Jiang L, Li X. Huang R, et al. Can J Cardiol. 2020 Nov;36(11):1782-1794. doi: 10.1016/j.cjca.2019.12.018. Epub 2019 Dec 28. Can J Cardiol. 2020. PMID: 32473103
Follow-up analysis identified the miR-532-3p-CSF2RA axis, as miR-532-3p downregulates CSF2RA via binding to CSF2RA's 3'UTR. ...In vivo, agomiR-532-3p therapy suppressed murine plaque formation and promoted plaque stabilization in a Csf2ra-dependent man …
Follow-up analysis identified the miR-532-3p-CSF2RA axis, as miR-532-3p downregulates CSF2RA via binding to CSF2RA's 3' …
A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption.
Shima K, Arumugam P, Sallese A, Horio Y, Ma Y, Trapnell C, Wessendarp M, Chalk C, McCarthy C, Carey BC, Trapnell BC, Suzuki T. Shima K, et al. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L438-L448. doi: 10.1152/ajplung.00175.2021. Epub 2022 Jan 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35043685 Free PMC article.
Because hPAP is caused by CSF2RA mutations in most patients, we created an animal model of hPAP caused by Csf2ra gene disruption (Csf2ra(-/-) mice) and evaluated the effects on AMs and lungs. ...In contrast, Csf2ra(+/-) mice had functionally normal AMs …
Because hPAP is caused by CSF2RA mutations in most patients, we created an animal model of hPAP caused by Csf2ra gene disrupti …
Disruption of CSF2RA in the bovine preimplantation embryo reduces development and affects embryonic gene expression in utero.
Sosa F, Uh K, Drum JN, Stoecklein KS, Davenport KM, Ortega MS, Lee K, Hansen PJ. Sosa F, et al. Reprod Fertil. 2023 Mar 1;4(2):e230001. doi: 10.1530/RAF-23-0001. Online ahead of print. Reprod Fertil. 2023. PMID: 37000631 Free PMC article.
The hypothesis that CSF2 plays a role in the preimplantation development of the bovine embryo was tested by evaluating consequences of inactivation of CSF2RA (the functional receptor in the embryo) for development of embryos in utero. CRISPR/Cas9 was used to alter sequence …
The hypothesis that CSF2 plays a role in the preimplantation development of the bovine embryo was tested by evaluating consequences of inact …
Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency.
Hetzel M, Suzuki T, Hashtchin AR, Arumugam P, Carey B, Schwabbauer M, Kuhn A, Meyer J, Schambach A, Van Der Loo J, Moritz T, Trapnell BC, Lachmann N. Hetzel M, et al. Hum Gene Ther Methods. 2017 Dec;28(6):318-329. doi: 10.1089/hgtb.2017.092. Epub 2017 Aug 30. Hum Gene Ther Methods. 2017. PMID: 28854814 Free PMC article.
Using a novel cell line constructed to express a normal GM-CSF receptor beta subunit and a dysfunctional alpha subunit (due to a function-altering CSF2RA(G196R) mutation) that reflects the macrophage disease phenotype of hPAP patients, it was demonstrated that Lv.EFS.CS …
Using a novel cell line constructed to express a normal GM-CSF receptor beta subunit and a dysfunctional alpha subunit (due to a function-al …
Gene therapy of Csf2ra deficiency in mouse fetal monocyte precursors restores alveolar macrophage development and function.
Li F, Okreglicka KM, Piattini F, Pohlmeier LM, Schneider C, Kopf M. Li F, et al. JCI Insight. 2022 Apr 8;7(7):e152271. doi: 10.1172/jci.insight.152271. JCI Insight. 2022. PMID: 35393945 Free PMC article.
CSF2-cFLiMo retained the capacity to develop into bona fide alveolar macrophages upon transfer into Csf2ra-/- neonates and prevented development of alveolar proteinosis and accumulation of apoptotic cells for at least 1 year in vivo. ...Harnessing the potential of this app …
CSF2-cFLiMo retained the capacity to develop into bona fide alveolar macrophages upon transfer into Csf2ra-/- neonates and prevented …
123 results