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2002 1
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46 results

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Page 1
The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection.
Schor S, Pu S, Nicolaescu V, Azari S, Kõivomägi M, Karim M, Cassonnet P, Saul S, Neveu G, Yueh A, Demeret C, Skotheim JM, Jacob Y, Randall G, Einav S. Schor S, et al. J Biol Chem. 2022 Jun;298(6):101956. doi: 10.1016/j.jbc.2022.101956. Epub 2022 Apr 20. J Biol Chem. 2022. PMID: 35452674 Free PMC article.
Our experiments indicated that BIKE catalyzes phosphorylation of a threonine 294 CLINT1 residue both in vitro and in cell culture. Our findings revealed that CLINT1 phosphorylation mediates its binding to the DENV nonstructural 3 protein and subsequently promotes DE …
Our experiments indicated that BIKE catalyzes phosphorylation of a threonine 294 CLINT1 residue both in vitro and in cell culture. Ou …
The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish.
Dodd ME, Hatzold J, Mathias JR, Walters KB, Bennin DA, Rhodes J, Kanki JP, Look AT, Hammerschmidt M, Huttenlocher A. Dodd ME, et al. Development. 2009 Aug;136(15):2591-600. doi: 10.1242/dev.038448. Epub 2009 Jul 1. Development. 2009. PMID: 19570844 Free PMC article.
The defects in clint1 mutants can be rescued by expression of zebrafish clint1 and can be phenocopied with clint1-specific morpholinos, supporting an essential role for Clint1 in epidermal development. Interaction studies suggest that Clint1 and …
The defects in clint1 mutants can be rescued by expression of zebrafish clint1 and can be phenocopied with clint1-speci …
Functional characterisation of romeharsha and clint1 reaffirms the link between plasma membrane homeostasis, cell size maintenance and tissue homeostasis in developing zebrafish epidermis.
Phatak M, Sonawane M. Phatak M, et al. J Biosci. 2018 Sep;43(4):605-619. J Biosci. 2018. PMID: 30207308
Here we have identified two more genetic conditions, romeharsha mutant and clint1 knockdown, in which membrane homeostasis is perturbed, as evident by increased endocytosis and accumulation of lysosomes. ...We further show that decreasing endocytosis in romeharsha mutant a …
Here we have identified two more genetic conditions, romeharsha mutant and clint1 knockdown, in which membrane homeostasis is perturb …
Gamma-Aminobutyric Acid Type A Receptor Subunit Pi is a potential chemoresistance regulator in colorectal cancer.
Wang T, Zhen Q, Wu T, Jin L, Yao S, Feng Y, Chen J, Chen C, Huang Z. Wang T, et al. Mol Biol Rep. 2023 Apr;50(4):3167-3177. doi: 10.1007/s11033-023-08268-w. Epub 2023 Jan 25. Mol Biol Rep. 2023. PMID: 36696022
The potential protein-protein interaction (PPI) network with GABRP was analyzed by the Search Tool for the Retrieval of Interaction Gene/Proteins (STRING) website. The PPI network predicted ANKRD66, CLINT1, HAP1, PLCL1, GABARPAP, GABARAPL1, NSF, GABARAPL2, TRAK2, and CLIC3 …
The potential protein-protein interaction (PPI) network with GABRP was analyzed by the Search Tool for the Retrieval of Interaction Gene/Pro …
Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis- and psoriasis-associated genes.
Sahlén P, Spalinskas R, Asad S, Mahapatra KD, Höjer P, Anil A, Eisfeldt J, Srivastava A, Nikamo P, Mukherjee A, Kim KH, Bergman O, Ståhle M, Sonkoly E, Pivarcsi A, Wahlgren CF, Nordenskjöld M, Taylan F, Bradley M, Tapia-Páez I. Sahlén P, et al. J Allergy Clin Immunol. 2021 May;147(5):1742-1752. doi: 10.1016/j.jaci.2020.09.035. Epub 2020 Oct 16. J Allergy Clin Immunol. 2021. PMID: 33069716 Free article.
Differential expression of 58 of the 118 target genes (49%) occurred in either AD or psoriatic lesions, many of which were not previously linked to any skin disease. We highlighted the genes AFG1L, CLINT1, ADO, LINC00302, and RP1-140J1.1 and provided further evidence for t …
Differential expression of 58 of the 118 target genes (49%) occurred in either AD or psoriatic lesions, many of which were not previously li …
PtdIns(4)P signalling and recognition systems.
Lenoir M, Overduin M. Lenoir M, et al. Adv Exp Med Biol. 2013;991:59-83. doi: 10.1007/978-94-007-6331-9_5. Adv Exp Med Biol. 2013. PMID: 23775691 Review.
Liquid facets-related (lqfR) is required for egg chamber morphogenesis during Drosophila oogenesis.
Leventis PA, Da Sylva TR, Rajwans N, Wasiak S, McPherson PS, Boulianne GL. Leventis PA, et al. PLoS One. 2011;6(10):e25466. doi: 10.1371/journal.pone.0025466. Epub 2011 Oct 17. PLoS One. 2011. PMID: 22043285 Free PMC article.
Clathrin interactor 1 [CLINT1] (also called enthoprotin/EpsinR) is an Epsin N-terminal homology (ENTH) domain-containing adaptor protein that functions in anterograde and retrograde clathrin-mediated trafficking between the trans-Golgi network and the endosome. ...Similarl …
Clathrin interactor 1 [CLINT1] (also called enthoprotin/EpsinR) is an Epsin N-terminal homology (ENTH) domain-containing adaptor prot …
Direct targets of pSTAT5 signalling in erythropoiesis.
Gillinder KR, Tuckey H, Bell CC, Magor GW, Huang S, Ilsley MD, Perkins AC. Gillinder KR, et al. PLoS One. 2017 Jul 21;12(7):e0180922. doi: 10.1371/journal.pone.0180922. eCollection 2017. PLoS One. 2017. PMID: 28732065 Free PMC article.
We identified known direct pSTAT5 target genes such as Bcl2l1, Pim1 and Cish, and many new targets likely to be involved in driving erythroid cell differentiation including those involved in mRNA splicing (Rbm25), epigenetic regulation (Suv420h2), and EpoR turnover (Clint1 …
We identified known direct pSTAT5 target genes such as Bcl2l1, Pim1 and Cish, and many new targets likely to be involved in driving erythroi …
Integrated bioinformatics analysis identifies established and novel TGFβ1-regulated genes modulated by anti-fibrotic drugs.
Wilson AC, Chiles J, Ashish S, Chanda D, Kumar PL, Mobley JA, Neptune ER, Thannickal VJ, McDonald MN. Wilson AC, et al. Sci Rep. 2022 Feb 23;12(1):3080. doi: 10.1038/s41598-022-07151-1. Sci Rep. 2022. PMID: 35197532 Free PMC article.
Specifically, four genes (BASP1, HSD17B6, CDH11, and TNS1) have been associated with pirfenidone, while five genes (CLINT1, CADM1, MTDH, SYDE1, and MCTS1) have been associated with nintedanib, and MYDGF has been implicated with treatment using both drugs. ...
Specifically, four genes (BASP1, HSD17B6, CDH11, and TNS1) have been associated with pirfenidone, while five genes (CLINT1, CADM1, MT …
46 results