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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1997 4
1998 5
1999 9
2000 9
2001 34
2002 47
2003 46
2004 53
2005 57
2006 64
2007 60
2008 76
2009 63
2010 88
2011 97
2012 90
2013 84
2014 98
2015 98
2016 102
2017 106
2018 129
2019 117
2020 140
2021 155
2022 121
2023 125
2024 51

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1,850 results

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Page 1
CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells.
Feng G, Bajpai G, Ma P, Koenig A, Bredemeyer A, Lokshina I, Lai L, Förster I, Leuschner F, Kreisel D, Lavine KJ. Feng G, et al. Circulation. 2022 Mar 8;145(10):765-782. doi: 10.1161/CIRCULATIONAHA.121.055888. Epub 2022 Feb 3. Circulation. 2022. PMID: 35113652 Free PMC article.
We observed increased abundance of regulatory T cells (Tregs) in the myocardium of injured Ccl17 knockout mice. CCL17 inhibited Treg recruitment through biased activation of CCR4. ...CCL17 competitively inhibited CCL22 stimulated ARRB signaling and Treg migra …
We observed increased abundance of regulatory T cells (Tregs) in the myocardium of injured Ccl17 knockout mice. CCL17 inhibite …
CCL17/TARC in autoimmunity and inflammation-not just a T-cell chemokine.
Lupancu TJ, Eivazitork M, Hamilton JA, Achuthan AA, Lee KM. Lupancu TJ, et al. Immunol Cell Biol. 2023 Aug;101(7):600-609. doi: 10.1111/imcb.12644. Epub 2023 Apr 25. Immunol Cell Biol. 2023. PMID: 36975092 Review.
Reference is made, for example, to recent literature indicating a role for CCL17 in the control of pain as part of a granulocyte macrophage-colony-stimulating factor/CCL17 pathway in lymphocyte-independent models and thus not as a T-cell chemokine. The review also d …
Reference is made, for example, to recent literature indicating a role for CCL17 in the control of pain as part of a granulocyte macr …
CCL17 acts as a novel therapeutic target in pathological cardiac hypertrophy and heart failure.
Zhang Y, Ye Y, Tang X, Wang H, Tanaka T, Tian R, Yang X, Wang L, Xiao Y, Hu X, Jin Y, Pang H, Du T, Liu H, Sun L, Xiao S, Dong R, Ferrucci L, Tian Z, Zhang S. Zhang Y, et al. J Exp Med. 2022 Aug 1;219(8):e20200418. doi: 10.1084/jem.20200418. Epub 2022 Jun 10. J Exp Med. 2022. PMID: 35687056 Free PMC article.
Serum proteomic profiling of an age-stratified healthy population and further community-based cohort together with heart failure patients study demonstrated that circulating C-C motif chemokine ligand 17 (CCL17) level increased with age and correlated with cardiac dysfunct …
Serum proteomic profiling of an age-stratified healthy population and further community-based cohort together with heart failure patients st …
What does elevated TARC/CCL17 expression tell us about eosinophilic disorders?
Catherine J, Roufosse F. Catherine J, et al. Semin Immunopathol. 2021 Jun;43(3):439-458. doi: 10.1007/s00281-021-00857-w. Epub 2021 May 19. Semin Immunopathol. 2021. PMID: 34009399 Free PMC article. Review.
Herein, the contribution of the chemo-attractant molecule thymus and activation-regulated chemokine (TARC/CCL17) to type 2 immunity will be reviewed. The clinical relevance of this chemokine and its target, C-C chemokine receptor 4 (CCR4), will be illustrated in the settin …
Herein, the contribution of the chemo-attractant molecule thymus and activation-regulated chemokine (TARC/CCL17) to type 2 immunity w …
CCL17 acts as an antitumor chemokine in micromilieu-driven immune skewing.
Li Y, Cao H, Jiang Z, Yan K, Shi J, Wang S, Wang F, Wang W, Li X, Sun N, Liu L, Chen L, Chen Y, Guo R, Song Y. Li Y, et al. Int Immunopharmacol. 2023 May;118:110078. doi: 10.1016/j.intimp.2023.110078. Epub 2023 Mar 29. Int Immunopharmacol. 2023. PMID: 37001380
RESULTS: The active CCL17/CCL22-CCR4 axis is a distinctive feature of the Hodgkin lymphoma microenvironment. ...Clinical survival outcomes of target gene (CCL17, CCL22, and CCR4) expression also identified that CCL17/CCL22-CCR4 axis is not a marker of poor pr …
RESULTS: The active CCL17/CCL22-CCR4 axis is a distinctive feature of the Hodgkin lymphoma microenvironment. ...Clinical survival out …
Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17.
Zhang A, Xu Y, Xu H, Ren J, Meng T, Ni Y, Zhu Q, Zhang WB, Pan YB, Jin J, Bi Y, Wu ZB, Lin S, Lou M. Zhang A, et al. Theranostics. 2021 Feb 6;11(8):3839-3852. doi: 10.7150/thno.53749. eCollection 2021. Theranostics. 2021. PMID: 33664865 Free PMC article.
Moreover, lactate secreted from PA cells facilitated M2 polarization via the mTORC2 and ERK signaling pathways, while activated TAMs secreted CCL17 to promote PA invasion via the CCL17/CCR4/mTORC1 axis. According to univariate analysis of clinical data, high CCL1 …
Moreover, lactate secreted from PA cells facilitated M2 polarization via the mTORC2 and ERK signaling pathways, while activated TAMs secrete …
The GM-CSF/CCL17 pathway in obesity-associated osteoarthritic pain and disease in mice.
Shin H, Prasad V, Lupancu T, Malik S, Achuthan A, Biondo M, Kingwell BA, Thiem M, Gottschalk M, Weighardt H, Förster I, de Steiger R, Hamilton JA, Lee KM. Shin H, et al. Osteoarthritis Cartilage. 2023 Oct;31(10):1327-1341. doi: 10.1016/j.joca.2023.05.008. Epub 2023 May 22. Osteoarthritis Cartilage. 2023. PMID: 37225052
OBJECTIVES: We have previously identified a granulocyte macrophage-colony stimulating factor (GM-CSF)/C-C motif ligand 17 (CCL17) pathway in monocytes/macrophages, in which GM-CSF regulates the formation of CCL17, and it is important for an experimental osteoarthrit …
OBJECTIVES: We have previously identified a granulocyte macrophage-colony stimulating factor (GM-CSF)/C-C motif ligand 17 (CCL17) pat …
CCL17 drives fibroblast activation in the progression of pulmonary fibrosis by enhancing the TGF-beta/Smad signaling.
Wang QR, Liu SS, Min JL, Yin M, Zhang Y, Zhang Y, Tang XN, Li X, Liu SS. Wang QR, et al. Biochem Pharmacol. 2023 Apr;210:115475. doi: 10.1016/j.bcp.2023.115475. Epub 2023 Mar 2. Biochem Pharmacol. 2023. PMID: 36870575
However, the source and function of CCL17 in PF remain unclear. Here, we demonstrated that the levels of CCL17 were increased in the lungs of IPF patients and mice with bleomycin (BLM)-induced PF. In particular, CCL17 were upregulated in alveolar macrophages …
However, the source and function of CCL17 in PF remain unclear. Here, we demonstrated that the levels of CCL17 were increased …
CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells.
Feng G, Zhu C, Lin CY, Bredemeyer A, Förster I, Kreisel D, Lavine KJ. Feng G, et al. J Am Heart Assoc. 2023 Feb 21;12(4):e028442. doi: 10.1161/JAHA.122.028442. Epub 2023 Feb 8. J Am Heart Assoc. 2023. PMID: 36752267 Free PMC article.
Methods and Results Mouse encephalomyocarditis virus was used to investigate the function of CCL17 in a viral myocarditis model. Ccl17(Gfp) reporter and knockout mice were used to identify the cell types that express CCL17 and delineate the functional importa …
Methods and Results Mouse encephalomyocarditis virus was used to investigate the function of CCL17 in a viral myocarditis model. C …
1,850 results