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Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation.
Horton AJ, Brooker J, Streitfeld WS, Flessa ME, Pillai B, Simpson R, Clark CD, Gooz MB, Sutton KK, Foley AC, Lee KH. Horton AJ, et al. Sci Rep. 2019 Feb 11;9(1):1738. doi: 10.1038/s41598-019-39078-5. Sci Rep. 2019. PMID: 30742009 Free PMC article.
We have found that Nkx2-5 positively and directly regulates a novel target gene, Ccdc117, in cells of the SHF at these stages. The nuclear/mitotic spindle associated protein Ccdc117 interacts with the MIP18/MMS19 cytoplasmic iron-sulfur (FeS) cluster assembly (CIA) …
We have found that Nkx2-5 positively and directly regulates a novel target gene, Ccdc117, in cells of the SHF at these stages. The nu …
Acute transcriptomic changes in murine RAW 264.7 cells following pseudorabies virus infection.
Tong C, Fu PF, Ming SL, Zeng L, Zhu HS, Wang J. Tong C, et al. Arch Virol. 2022 Dec;167(12):2623-2631. doi: 10.1007/s00705-022-05598-1. Epub 2022 Oct 21. Arch Virol. 2022. PMID: 36269412
In total, 156, 153, and 190 differentially expressed genes were identified at 2 h, 12 h, and 36 h, respectively. Seven differentially expressed genes (Trim27, Ccdc117, Mrps12, Ccl4, Cerkl, Ubald1, and Hmga1-rs1) were present across all treatment groups. ...
In total, 156, 153, and 190 differentially expressed genes were identified at 2 h, 12 h, and 36 h, respectively. Seven differentially expres …
Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development.
Wang Y, Zhou T, Wan J, Yang Y, Chen X, Wang J, Zhou C, Liu M, Ling X, Zhang J. Wang Y, et al. Oncotarget. 2016 Aug 16;7(33):53772-53782. doi: 10.18632/oncotarget.10741. Oncotarget. 2016. PMID: 27449102 Free PMC article.
We identified 19 genes encoding putative miR-29b target transcripts. These included Zbtb40, Hbp1, Ccdc117, Ypel2, Klf4, and Tmed9, which are upregulated at the 4-cell state of mouse development concomitant with miR-29b downregulation. Luciferase reporter analysis confirmed …
We identified 19 genes encoding putative miR-29b target transcripts. These included Zbtb40, Hbp1, Ccdc117, Ypel2, Klf4, and Tmed9, wh …
Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis.
Chen YP, Jin X, Xiang Z, Chen SH, Li YM. Chen YP, et al. Liver Int. 2013 Sep;33(8):1257-65. doi: 10.1111/liv.12196. Epub 2013 May 20. Liver Int. 2013. PMID: 23682678
For down-regulated miRNAs, 86 GO and 104 KEGG pathways were enriched, including fatty acid metabolism and insulin signalling pathway. Besides, Ccdc117, Gcom1, Zmynd11 and Zfp423 were found at top list as under common regulation of maximum miRNAs. ...
For down-regulated miRNAs, 86 GO and 104 KEGG pathways were enriched, including fatty acid metabolism and insulin signalling pathway. Beside …
A multi-breed GWAS for morphometric traits in four Beninese indigenous cattle breeds reveals loci associated with conformation, carcass and adaptive traits.
Vanvanhossou SFU, Scheper C, Dossa LH, Yin T, Brügemann K, König S. Vanvanhossou SFU, et al. BMC Genomics. 2020 Nov 11;21(1):783. doi: 10.1186/s12864-020-07170-0. BMC Genomics. 2020. PMID: 33176675 Free PMC article.
According to their functional annotations, detected potential candidate genes were associated with stress or immune response (genes PTAFR, PBRM1, ADAMTS12) and with feed efficiency (genes MEGF11 SLC16A4, CCDC117). CONCLUSIONS: Accurate measurements contributed to large SNP …
According to their functional annotations, detected potential candidate genes were associated with stress or immune response (genes PTAFR, P …
Jarid2 is among a set of genes differentially regulated by Nkx2.5 during outflow tract morphogenesis.
Barth JL, Clark CD, Fresco VM, Knoll EP, Lee B, Argraves WS, Lee KH. Barth JL, et al. Dev Dyn. 2010 Jul;239(7):2024-33. doi: 10.1002/dvdy.22341. Dev Dyn. 2010. PMID: 20549724 Free PMC article.
Here, we define a set of genes (Lrrn1, Elovl2, Safb, Slc39a6, Khdrbs1, Hoxb4, Fez1, Ccdc117, Jarid2, Nrcam, and Enpp3) expressed in SHF containing pharyngeal arch tissue whose regulation is dependent on Nkx2.5. ...
Here, we define a set of genes (Lrrn1, Elovl2, Safb, Slc39a6, Khdrbs1, Hoxb4, Fez1, Ccdc117, Jarid2, Nrcam, and Enpp3) expressed in S …