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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1977 2
1980 1
1982 1
1983 2
1984 6
1985 3
1986 1
1987 1
1989 1
1992 1
1993 1
1994 2
1996 1
1997 1
2000 1
2001 1
2003 2
2004 1
2005 2
2006 2
2007 4
2008 4
2010 3
2011 3
2012 1
2013 1
2015 1
2016 1
2017 2
2018 5
2019 2
2020 5
2021 5
2022 5
2023 4
2024 0

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73 results

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Page 1
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells.
Hendel A, Bak RO, Clark JT, Kennedy AB, Ryan DE, Roy S, Steinfeld I, Lunstad BD, Kaiser RJ, Wilkens AB, Bacchetta R, Tsalenko A, Dellinger D, Bruhn L, Porteus MH. Hendel A, et al. Among authors: bruhn l. Nat Biotechnol. 2015 Sep;33(9):985-989. doi: 10.1038/nbt.3290. Epub 2015 Jun 29. Nat Biotechnol. 2015. PMID: 26121415 Free PMC article.
Predicting the HbA1c level following glucose-lowering interventions in individuals with HbA1c-defined prediabetes: a post-hoc analysis from the randomized controlled PRE-D trial.
Bruhn L, Vistisen D, Amadid H, Clemmensen KKB, Karstoft K, Ried-Larsen M, Persson F, Jørgensen ME, Møller CL, Stallknecht B, Færch K, Blond MB. Bruhn L, et al. Endocrine. 2023 Jul;81(1):67-76. doi: 10.1007/s12020-023-03384-w. Epub 2023 May 17. Endocrine. 2023. PMID: 37198379 Clinical Trial.
Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs.
Ryan DE, Taussig D, Steinfeld I, Phadnis SM, Lunstad BD, Singh M, Vuong X, Okochi KD, McCaffrey R, Olesiak M, Roy S, Yung CW, Curry B, Sampson JR, Bruhn L, Dellinger DJ. Ryan DE, et al. Among authors: bruhn l. Nucleic Acids Res. 2018 Jan 25;46(2):792-803. doi: 10.1093/nar/gkx1199. Nucleic Acids Res. 2018. PMID: 29216382 Free PMC article.
Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors.
Ryan DE, Diamant-Levi T, Steinfeld I, Taussig D, Visal-Shah S, Thakker S, Lunstad BD, Kaiser RJ, McCaffrey R, Ortiz M, Townsend J, Welch WRW, Singh M, Curry B, Dellinger DJ, Bruhn L. Ryan DE, et al. Among authors: bruhn l. Biochemistry. 2023 Dec 19;62(24):3512-3520. doi: 10.1021/acs.biochem.1c00768. Epub 2022 Apr 18. Biochemistry. 2023. PMID: 35436085 Free PMC article.
RNA-protein analysis using a conditional CRISPR nuclease.
Lee HY, Haurwitz RE, Apffel A, Zhou K, Smart B, Wenger CD, Laderman S, Bruhn L, Doudna JA. Lee HY, et al. Among authors: bruhn l. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5416-21. doi: 10.1073/pnas.1302807110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493562 Free PMC article.
Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle.
Hingst JR, Bruhn L, Hansen MB, Rosschou MF, Birk JB, Fentz J, Foretz M, Viollet B, Sakamoto K, Færgeman NJ, Havelund JF, Parker BL, James DE, Kiens B, Richter EA, Jensen J, Wojtaszewski JFP. Hingst JR, et al. Among authors: bruhn l. Mol Metab. 2018 Oct;16:24-34. doi: 10.1016/j.molmet.2018.07.001. Epub 2018 Jul 25. Mol Metab. 2018. PMID: 30093357 Free PMC article.
73 results