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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1937 1
1975 2
1976 1
1977 4
1978 5
1979 7
1980 5
1981 7
1982 6
1983 7
1984 11
1985 8
1986 6
1987 9
1988 22
1989 20
1990 35
1991 51
1992 51
1993 75
1994 109
1995 117
1996 182
1997 204
1998 250
1999 316
2000 340
2001 435
2002 449
2003 578
2004 584
2005 681
2006 789
2007 833
2008 913
2009 959
2010 1032
2011 1149
2012 1217
2013 1359
2014 1287
2015 1330
2016 1386
2017 1362
2018 1309
2019 1368
2020 1329
2021 1328
2022 1202
2023 1131
2024 296

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23,242 results

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Page 1
The BMP Pathway and Its Inhibitors in the Skeleton.
Lowery JW, Rosen V. Lowery JW, et al. Physiol Rev. 2018 Oct 1;98(4):2431-2452. doi: 10.1152/physrev.00028.2017. Physiol Rev. 2018. PMID: 30156494 Free article. Review.
Defects in the BMP pathway or its regulation underlie multiple human diseases of different organ systems. ...We frame the content of the review around major unanswered questions for which incomplete evidence is available. First, we consider the gene regulatory network down …
Defects in the BMP pathway or its regulation underlie multiple human diseases of different organ systems. ...We frame the content of …
TGF-beta and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease.
Wu M, Chen G, Li YP. Wu M, et al. Bone Res. 2016 Apr 26;4:16009. doi: 10.1038/boneres.2016.9. eCollection 2016. Bone Res. 2016. PMID: 27563484 Free PMC article. Review.
Dysregulated TGF-beta and BMP signaling result in a number of bone disorders in humans. Knockout or mutation of TGF-beta and BMP signaling-related genes in mice leads to bone abnormalities of varying severity, which enable a better understanding of TGF-beta/BMP
Dysregulated TGF-beta and BMP signaling result in a number of bone disorders in humans. Knockout or mutation of TGF-beta and BMP
Application of BMP in Bone Tissue Engineering.
Zhu L, Liu Y, Wang A, Zhu Z, Li Y, Zhu C, Che Z, Liu T, Liu H, Huang L. Zhu L, et al. Front Bioeng Biotechnol. 2022 Mar 31;10:810880. doi: 10.3389/fbioe.2022.810880. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 35433652 Free PMC article. Review.
Current results show that BMPs can promote healing of bone defects and reduce the occurrence of complications. However, the mechanism of BMP in vivo still needs to be explored, and application of BMP alone to a bone defect site cannot achieve good therapeutic effect …
Current results show that BMPs can promote healing of bone defects and reduce the occurrence of complications. However, the mechanism of …
BMP signaling during craniofacial development: new insights into pathological mechanisms leading to craniofacial anomalies.
Ueharu H, Mishina Y. Ueharu H, et al. Front Physiol. 2023 May 18;14:1170511. doi: 10.3389/fphys.2023.1170511. eCollection 2023. Front Physiol. 2023. PMID: 37275223 Free PMC article. Review.
We and others have reported that abnormalities in BMP signaling in cranial NCCs develop CFAs in mice. Abnormal levels of BMP signaling cause miscorrelation with other signaling pathways such as Wnt signaling and FGF signaling, which mutations in the signaling pathwa …
We and others have reported that abnormalities in BMP signaling in cranial NCCs develop CFAs in mice. Abnormal levels of BMP s …
Secreted BMP antagonists and their role in cancer and bone metastases.
Todd GM, Gao Z, Hyvönen M, Brazil DP, Ten Dijke P. Todd GM, et al. Bone. 2020 Aug;137:115455. doi: 10.1016/j.bone.2020.115455. Epub 2020 May 28. Bone. 2020. PMID: 32473315 Review.
The interaction of BMP ligand with its receptors is carefully controlled by a diverse set of secreted antagonists that bind BMPs and block their interaction with their cognate BMP receptors. Perturbations in this BMP/BMP antagonist balance are implicat …
The interaction of BMP ligand with its receptors is carefully controlled by a diverse set of secreted antagonists that bind BMPs and …
BMP Signaling in the Development and Regeneration of Cranium Bones and Maintenance of Calvarial Stem Cells.
Chen G, Xu H, Yao Y, Xu T, Yuan M, Zhang X, Lv Z, Wu M. Chen G, et al. Front Cell Dev Biol. 2020 Mar 10;8:135. doi: 10.3389/fcell.2020.00135. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32211409 Free PMC article. Review.
Following the inherent evidence of BMP signaling in craniofacial biology, we summarize recent discoveries relating to BMP signaling in the development of calvarial structures, functions of the suture stem cells and their niche and regeneration. This review will not …
Following the inherent evidence of BMP signaling in craniofacial biology, we summarize recent discoveries relating to BMP sign …
Recent progress in the biology and physiology of BMP-8a.
Tang J, Tan M, Liao S, Pang M, Li J. Tang J, et al. Connect Tissue Res. 2023 May;64(3):219-228. doi: 10.1080/03008207.2022.2160326. Epub 2023 Jan 2. Connect Tissue Res. 2023. PMID: 36594156 Review.
BMP-8a is also a member of the BMP family of proteins that regulates chondrogenesis and osteogenesis. In addition to its osteoinductive capabilities, BMP-8a is involved in the progression of diverse cancers....
BMP-8a is also a member of the BMP family of proteins that regulates chondrogenesis and osteogenesis. In addition to its osteo
Modulation of BMP signalling by integrins.
Ashe HL. Ashe HL. Biochem Soc Trans. 2016 Oct 15;44(5):1465-1473. doi: 10.1042/BST20160111. Biochem Soc Trans. 2016. PMID: 27911728 Review.
In this review, I describe various examples of modulation of the BMP pathway by integrins. In the case of the Drosophila embryo and some cell line-based studies, integrins have been found to enhance BMP responses through different mechanisms, such as enhancement of …
In this review, I describe various examples of modulation of the BMP pathway by integrins. In the case of the Drosophila embryo and s …
BMP signaling and its modifiers in kidney development.
Nishinakamura R, Sakaguchi M. Nishinakamura R, et al. Pediatr Nephrol. 2014 Apr;29(4):681-6. doi: 10.1007/s00467-013-2671-9. Epub 2013 Nov 12. Pediatr Nephrol. 2014. PMID: 24217785 Review.
During mid-gestation, BMP7 maintains the nephron progenitors and, at the same time, sensitizes them to the ureteric bud-derived differentiation signal. Crossveinless2 is a pro-BMP factor, and its absence leads to kidney hypoplasia. After birth, when nephron progenitors hav …
During mid-gestation, BMP7 maintains the nephron progenitors and, at the same time, sensitizes them to the ureteric bud-derived differentiat …
BMP signaling: A significant player and therapeutic target for osteoarthritis.
Jaswal AP, Kumar B, Roelofs AJ, Iqbal SF, Singh AK, Riemen AHK, Wang H, Ashraf S, Nanasaheb SV, Agnihotri N, De Bari C, Bandyopadhyay A. Jaswal AP, et al. Osteoarthritis Cartilage. 2023 Nov;31(11):1454-1468. doi: 10.1016/j.joca.2023.05.016. Epub 2023 Jun 29. Osteoarthritis Cartilage. 2023. PMID: 37392862
RESULTS: Upon induction of OA, depletion of SMURF1-an intra-cellular BMP signaling inhibitor in articular cartilage coincided with the activation of BMP signaling, as measured by pSMAD1/5/9 expression. ...CONCLUSION: Our findings showed that BMP signaling is …
RESULTS: Upon induction of OA, depletion of SMURF1-an intra-cellular BMP signaling inhibitor in articular cartilage coincided with th …
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