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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1934 1
1960 1
1964 1
1965 1
1967 8
1968 4
1969 7
1970 11
1971 6
1972 10
1973 6
1974 9
1975 7
1976 9
1977 14
1978 9
1979 18
1980 11
1981 11
1982 15
1983 19
1984 19
1985 13
1986 22
1987 16
1988 17
1989 25
1990 17
1991 21
1992 26
1993 20
1994 25
1995 28
1996 34
1997 29
1998 44
1999 34
2000 29
2001 26
2002 32
2003 39
2004 39
2005 41
2006 43
2007 37
2008 51
2009 52
2010 62
2011 61
2012 53
2013 50
2014 58
2015 62
2016 59
2017 50
2018 49
2019 38
2020 36
2021 44
2022 51
2023 43
2024 13

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Search Results

1,543 results

Results by year

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Page 1
Single-cell census of human tooth development enables generation of human enamel.
Alghadeer A, Hanson-Drury S, Patni AP, Ehnes DD, Zhao YT, Li Z, Phal A, Vincent T, Lim YC, O'Day D, Spurrell CH, Gogate AA, Zhang H, Devi A, Wang Y, Starita L, Doherty D, Glass IA, Shendure J, Freedman BS, Baker D, Regier MC, Mathieu J, Ruohola-Baker H. Alghadeer A, et al. Dev Cell. 2023 Oct 23;58(20):2163-2180.e9. doi: 10.1016/j.devcel.2023.07.013. Epub 2023 Aug 14. Dev Cell. 2023. PMID: 37582367
However, the enamel is gradually damaged or partially lost in over 90% of adults and cannot be regenerated due to a lack of ameloblasts in erupted teeth. Here, we use single-cell combinatorial indexing RNA sequencing (sci-RNA-seq) to establish a spatiotemporal single-cell …
However, the enamel is gradually damaged or partially lost in over 90% of adults and cannot be regenerated due to a lack of ameloblasts …
HIF-2alpha Inhibits Ameloblast Differentiation via Hey2 in Tooth Development.
Kimura S, Takeshita N, Oyanagi T, Seki D, Jiang W, Hidaka K, Fukumoto S, Takahashi I, Takano-Yamamoto T. Kimura S, et al. J Dent Res. 2022 Dec;101(13):1637-1644. doi: 10.1177/00220345221111971. Epub 2022 Jul 31. J Dent Res. 2022. PMID: 35912776
However, hypoxic state in tooth germs and the roles of HIF in ameloblast differentiation have not been understood. The aim of this study is to clarify the role of HIF in ameloblast differentiation during tooth germ development. ...These findings suggest that …
However, hypoxic state in tooth germs and the roles of HIF in ameloblast differentiation have not been understood. The aim of this st …
DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE.
Lacruz RS, Habelitz S, Wright JT, Paine ML. Lacruz RS, et al. Physiol Rev. 2017 Jul 1;97(3):939-993. doi: 10.1152/physrev.00030.2016. Physiol Rev. 2017. PMID: 28468833 Free PMC article. Review.
These heavily polarized cells form a monolayer around the developing enamel tissue and move as a single forming front in specified directions as they lay down a proteinaceous matrix that serves as a template for crystal growth. ...In this unique environment, amel …
These heavily polarized cells form a monolayer around the developing enamel tissue and move as a single forming front in specified di …
Control of ameloblast differentiation.
Zeichner-David M, Diekwisch T, Fincham A, Lau E, MacDougall M, Moradian-Oldak J, Simmer J, Snead M, Slavkin HC. Zeichner-David M, et al. Int J Dev Biol. 1995 Feb;39(1):69-92. Int J Dev Biol. 1995. PMID: 7626423 Free article. Review.
This review highlights a number of advances towards understanding the sequential developmental cascade of events beginning in the oral ectodermally-derived odontogenic placode and culminating in the formation of the mineralized enamel extracellular matrix. Recent discoveries of …
This review highlights a number of advances towards understanding the sequential developmental cascade of events beginning in the oral ectod …
Autophagy Plays a Crucial Role in Ameloblast Differentiation.
Iwaya C, Suzuki A, Shim J, Ambrose CG, Iwata J. Iwaya C, et al. J Dent Res. 2023 Aug;102(9):1047-1057. doi: 10.1177/00220345231169220. Epub 2023 May 30. J Dent Res. 2023. PMID: 37249312 Free PMC article.
Tooth enamel is generated by ameloblasts. Any failure in amelogenesis results in defects in the enamel, a condition known as amelogenesis imperfecta. ...Taken together, our findings indicate that autophagy plays a crucial role in ameloblast differentiation and that …
Tooth enamel is generated by ameloblasts. Any failure in amelogenesis results in defects in the enamel, a condition known as amelogen …
Partial epithelial-mesenchymal transition during enamel development.
Bazina F, Brouxhon SM, Kyrkanides S. Bazina F, et al. Clin Exp Dent Res. 2022 Apr;8(2):513-518. doi: 10.1002/cre2.543. Epub 2022 Feb 19. Clin Exp Dent Res. 2022. PMID: 35182458 Free PMC article.
OBJECTIVES: We set out to investigate whether a hybrid stem-like p-EMT phenotype develops during murine molar enamel development in vivo. SETTING AND SAMPLE POPULATION: Histology specimens incorporating molar tooth buds harvested from mice at post-natal day 4 (P4) w …
OBJECTIVES: We set out to investigate whether a hybrid stem-like p-EMT phenotype develops during murine molar enamel development …
PER2-mediated ameloblast differentiation via PPARgamma/AKT1/beta-catenin axis.
Huang W, Zheng X, Yang M, Li R, Song Y. Huang W, et al. Int J Oral Sci. 2021 May 19;13(1):16. doi: 10.1038/s41368-021-00123-7. Int J Oral Sci. 2021. PMID: 34011974 Free PMC article.
Circadian rhythm is involved in the development and diseases of many tissues. However, as an essential environmental regulating factor, its effect on amelogenesis has not been fully elucidated. The present study aims to investigate the correlation between circadian rhythm …
Circadian rhythm is involved in the development and diseases of many tissues. However, as an essential environmental regulating facto …
Organoids from mouse molar and incisor as new tools to study tooth-specific biology and development.
Hermans F, Hemeryck L, Bueds C, Torres Pereiro M, Hasevoets S, Kobayashi H, Lambrechts D, Lambrichts I, Bronckaers A, Vankelecom H. Hermans F, et al. Stem Cell Reports. 2023 May 9;18(5):1166-1181. doi: 10.1016/j.stemcr.2023.03.011. Epub 2023 Apr 20. Stem Cell Reports. 2023. PMID: 37084723 Free PMC article.
Organoid models provide powerful tools to study tissue biology and development in a dish. Presently, organoids have not yet been developed from mouse tooth. ...Single-cell transcriptomics supports this developmental potential and reveals co-differentiation into junc …
Organoid models provide powerful tools to study tissue biology and development in a dish. Presently, organoids have not yet been d …
The hidden depths of zebrafish skin.
Tan YR, Liaw M, Chen CH. Tan YR, et al. Elife. 2023 May 23;12:e88597. doi: 10.7554/eLife.88597. Elife. 2023. PMID: 37218526 Free PMC article.
GSK3beta inhibitor-induced dental mesenchymal stem cells regulate ameloblast differentiation.
Yamada A, Yoshizaki K, Saito K, Ishikawa M, Chiba Y, Hoshikawa S, Chiba M, Hino R, Maruya Y, Sato H, Masuda K, Yamaza H, Nakamura T, Iwamoto T, Fukumoto S. Yamada A, et al. J Oral Biosci. 2022 Dec;64(4):400-409. doi: 10.1016/j.job.2022.10.002. Epub 2022 Oct 18. J Oral Biosci. 2022. PMID: 36270608
OBJECTIVES: Epithelial-mesenchymal interactions are extremely important in tooth development and essential for ameloblast differentiation, especially during tooth formation. We aimed to identify the type of mesenchymal cells important in ameloblast differenti …
OBJECTIVES: Epithelial-mesenchymal interactions are extremely important in tooth development and essential for ameloblast diff …
1,543 results