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Acetyl salicylic acid induces damage to intestinal epithelial cells by oxidation-related modifications of ZO-1.
Fukui A, Naito Y, Handa O, Kugai M, Tsuji T, Yoriki H, Qin Y, Adachi S, Higashimura Y, Mizushima K, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Yagi N, Kokura S, Yoshikawa T. Fukui A, et al. Am J Physiol Gastrointest Liver Physiol. 2012 Oct 15;303(8):G927-36. doi: 10.1152/ajpgi.00236.2012. Epub 2012 Aug 23. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22917627 Free article.
Acetyl salicylic acid (ASA) is one of the most frequently prescribed medications for the secondary prevention of cardiovascular and cerebrovascular events. ...Our findings indicate that ASA-induced ROS production can specifically modify the expression …
Acetyl salicylic acid (ASA) is one of the most frequently prescribed medications for the secondary prevention of cardio …
A review of the mechanism and prophylaxis of acetyl salicylic acid-induced injury of the small intestine.
Handa O, Takayama S, Mukai R, Suyama Y, Majima A, Fukui A, Omatsu T, Naito Y. Handa O, et al. Free Radic Res. 2018 Dec;52(11-12):1266-1270. doi: 10.1080/10715762.2018.1455003. Epub 2018 Apr 3. Free Radic Res. 2018. PMID: 29611728 Review.
Especially, a recent advancement in endoscopy revealed that aspirin-induced small intestinal mucosal injury is considerably higher than previously believed. ...These phenomena were suppressed by an antioxidant. Finally, we investigated the role of intestinal …
Especially, a recent advancement in endoscopy revealed that aspirin-induced small intestinal mucosal injury is considerably hi …