Histone H4 mRNA from the nematode Ascaris lumbricoides is cis-spliced and polyadenylated

Biochim Biophys Acta. 1997 Feb 28;1350(3):259-61. doi: 10.1016/s0167-4781(96)00235-7.

Abstract

A histone H4 gene from Ascaris lumbricoides contains an intron of approx. 2040 bp. Transcripts of the gene are spliced and polyadenylated. This is the first intron-containing H4 gene described for a metazoan. Notably, H4 mRNA from another nematode, Caenorhabditis elegans, is intron-less and lacks poly A (Roberts, S.B., Emmons, S.W. and Childs, G. (1989) J. Mol. Biol. 206, 567-577).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Ascaris lumbricoides / genetics*
  • Genes, Helminth / genetics
  • Histones / genetics*
  • Introns / genetics
  • Molecular Sequence Data
  • Poly A
  • RNA Splicing / physiology*
  • RNA, Messenger / genetics*
  • Restriction Mapping
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

Substances

  • Histones
  • RNA, Messenger
  • Poly A

Associated data

  • GENBANK/Z69289
  • GENBANK/Z69290