Abstract
A histone H4 gene from Ascaris lumbricoides contains an intron of approx. 2040 bp. Transcripts of the gene are spliced and polyadenylated. This is the first intron-containing H4 gene described for a metazoan. Notably, H4 mRNA from another nematode, Caenorhabditis elegans, is intron-less and lacks poly A (Roberts, S.B., Emmons, S.W. and Childs, G. (1989) J. Mol. Biol. 206, 567-577).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Ascaris lumbricoides / genetics*
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Genes, Helminth / genetics
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Histones / genetics*
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Introns / genetics
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Molecular Sequence Data
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Poly A
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RNA Splicing / physiology*
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RNA, Messenger / genetics*
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Restriction Mapping
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Sequence Analysis, DNA
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Sequence Homology, Nucleic Acid
Substances
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Histones
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RNA, Messenger
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Poly A
Associated data
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GENBANK/Z69289
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GENBANK/Z69290