Viral Related Tools against SARS-CoV-2

Viruses. 2020 Oct 16;12(10):1172. doi: 10.3390/v12101172.

Abstract

At the end of 2019, a new disease appeared and spread all over the world, the COVID-19, produced by the coronavirus SARS-CoV-2. As a consequence of this worldwide health crisis, the scientific community began to redirect their knowledge and resources to fight against it. Here we summarize the recent research on viruses employed as therapy and diagnostic of COVID-19: (i) viral-vector vaccines both in clinical trials and pre-clinical phases; (ii) the use of bacteriophages to find antibodies specific to this virus and some studies of how to use the bacteriophages themselves as a treatment against viral diseases; and finally, (iii) the use of CRISPR-Cas technology both to obtain a fast precise diagnose of the patient and also the possible use of this technology as a cure.

Keywords: COVID-19; CRISPR; SARS-CoV-2; diagnosis; phages; prevention; treatment; viruses.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antibodies, Viral / immunology
  • Antibodies, Viral / therapeutic use
  • Antiviral Agents / therapeutic use
  • Bacteriophages
  • Betacoronavirus / isolation & purification
  • COVID-19
  • CRISPR-Cas Systems
  • Coronavirus Infections / therapy*
  • Coronavirus Infections / virology*
  • Humans
  • Pandemics
  • Phage Therapy
  • Pneumonia, Viral / therapy*
  • Pneumonia, Viral / virology*
  • SARS-CoV-2
  • Viral Vaccines / immunology

Substances

  • Antibodies, Viral
  • Antiviral Agents
  • Viral Vaccines