Differences in the Interleukin-1β/Soluble ST2 Interplay Between Acute and Chronic Heart Failure

E Revuelta-López; J Lupón; A Lax; D A Pascual-Figal; A Bayés-Genís

doi:10.1007/s12265-020-09958-7

Differences in the Interleukin-1β/Soluble ST2 Interplay Between Acute and Chronic Heart Failure

J Cardiovasc Transl Res. 2020 Oct;13(5):864-866. doi: 10.1007/s12265-020-09958-7. Epub 2020 Jan 22.

Authors

E Revuelta-López^{1

2}, J Lupón^{2

3}, A Lax^{4

5}, D A Pascual-Figal^{2

4

5

6}, A Bayés-Genís^{7

8}

Affiliations

¹ Heart Failure and Cardiac Regeneration (ICREC) Research Program, Health Science Research Institute Germans Trias i Pujol (IGTP), Badalona, Spain.
² Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares, CIBERCV, Madrid, Spain.
³ Cardiology Service and Heart Failure Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
⁴ Cardiology Department, Hospital Virgen de la Arrixaca, Murcia, Spain.
⁵ Universidad de Murcia, Murcia, Spain.
⁶ Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain.
⁷ Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares, CIBERCV, Madrid, Spain. abayesgenis@gmail.com.
⁸ Cardiology Service and Heart Failure Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. abayesgenis@gmail.com.

PMID: 31970669
DOI: 10.1007/s12265-020-09958-7

Abstract

Recently, novel findings about the interleukin 1β (IL-1 β) axis in acute decompensated heart failure (ADHF) have been published. There is a positive correlation between IL-1 β and interleukin-1 receptor like 1 (sST2) in ADHF patients. Is there also a correlation between the values of IL-1 β and sST2 in chronic heart failure patients?

Keywords: Acute Decompensated Heart Failure; Chronic Heart Failure; Interleukin 1β; sST2.

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acute Disease
Aged
Aged, 80 and over
Biomarkers / blood
Chronic Disease
Female
Heart Failure / blood*
Heart Failure / diagnosis
Heart Failure / immunology
Humans
Interleukin-1 Receptor-Like 1 Protein / blood*
Interleukin-1beta / blood*
Male
Middle Aged
Prospective Studies

Substances

Biomarkers
IL1B protein, human
IL1RL1 protein, human
Interleukin-1 Receptor-Like 1 Protein
Interleukin-1beta