Deep eutectic solvents-derived carbon dots for detection of mercury (II), photocatalytic antifungal activity and fluorescent labeling for C. albicans

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Sep 5:220:117080. doi: 10.1016/j.saa.2019.04.072. Epub 2019 Apr 26.

Abstract

A novel nitrogen and chloride co-doped carbon dots (N/Cl-CDs) based choline chloride-urea deep eutectic solvents (DESs) were synthesized by one-step hydrothermal method with high quantum yield of 37% and excellent photoluminescent properties. This N/Cl-CDs fluorescent probe had been successfully applied to sensitively and selectively detect the concentration of Hg2+ with a linear range of 0.2-40 μM and a detection limit of 0.05 μM. Moreover, the N/Cl-CDs displayed a strong photocatalytic antifungal activity against C. albicans and their photoinduced antifungal functions were evaluated under conditions of varying other experimental parameters. The antifungal efficiency of N/Cl-CDs (7 mg/mL) against C. albicans is upon 100% when extending the visible light irradiation time to 80 min. In addition, the excellent luminescence properties of N/Cl-CDs can also label C. albicans and displayed multicolour fluorescence imaging at different excitation wavelengths. Based on their functions of fluorescence probe, antifungal and fluorescence imaging, N/Cl-CDs would provide potentials for a wide range of applications in the detection and microbe in the near future.

Keywords: Antifungal; Carbon dots; DESs; Fluorescent probe; Multicolour fluorescence.

MeSH terms

  • Antifungal Agents / pharmacology*
  • Candida albicans / chemistry
  • Candida albicans / drug effects
  • Carbon / chemistry
  • Chlorides / chemistry
  • Fluorescent Dyes / chemistry*
  • Light
  • Mercury / analysis*
  • Nitrogen / chemistry
  • Photochemical Processes
  • Photoelectron Spectroscopy
  • Quantum Dots / chemistry*
  • Solvents / chemistry*
  • Spectroscopy, Fourier Transform Infrared
  • Water Pollutants, Chemical / analysis

Substances

  • Antifungal Agents
  • Chlorides
  • Fluorescent Dyes
  • Solvents
  • Water Pollutants, Chemical
  • Carbon
  • Mercury
  • Nitrogen