European Restrictions on 1,2-Dichloroethane: C-H Activation Research and Development Should Be Liberated and not Limited

Angew Chem Int Ed Engl. 2018 Oct 22;57(43):14286-14290. doi: 10.1002/anie.201800549. Epub 2018 Sep 16.

Abstract

Plan B: 1,2-Dichloroethane was recently subject to regulatory controls in the European Union that will severely limit its commercial use. The practitioners of innovative synthetic methods, particularly C-H bond activation, need to investigate alternative solvents if their chemistry is to stay relevant.

Keywords: 1,2-dichloroethane; C−H activation; REACH; regulation; solvents.

MeSH terms

  • Ethylene Dichlorides / chemistry*
  • Solvents / chemistry*

Substances

  • Ethylene Dichlorides
  • Solvents
  • ethylene dichloride