Plan B: 1,2-Dichloroethane was recently subject to regulatory controls in the European Union that will severely limit its commercial use. The practitioners of innovative synthetic methods, particularly C-H bond activation, need to investigate alternative solvents if their chemistry is to stay relevant.
Keywords: 1,2-dichloroethane; C−H activation; REACH; regulation; solvents.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.