Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance. Part 2: Treatment

Drug Metab Rev. 2017 May;49(2):253-283. doi: 10.1080/03602532.2017.1307387. Epub 2017 Jun 19.

Abstract

Raman spectroscopy and surface-enhanced raman scattering (SERS) have the potential to improve the detection and monitoring of various diseases, particularly cancer, with or without the support of multifunctional active nanosystems. This review is focused on the recent advances that have made Raman a major tool for treatment guidance for surgical tumor resection or for analytical monitoring of various therapies, such as photodynamic therapy, photothermal therapy, and drug delivery. The potential of Raman spectroscopy and nanosytems to further improve cancer treatments is also discussed.

Keywords: Cancer; PDT; PTT; Raman; SERS; carbonaceous; drug; nanoparticles; plasmonic; treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Humans
  • Nanoparticles*
  • Nanotubes, Carbon*
  • Neoplasms / diagnosis
  • Neoplasms / therapy*
  • Spectrum Analysis, Raman / methods*
  • Surface Plasmon Resonance / methods

Substances

  • Nanotubes, Carbon