Novel coumarin-based fluorescent probe for selective detection of Cu(II)

Ahmadreza Bekhradnia; Elham Domehri; Masome Khosravi

doi:10.1016/j.saa.2015.07.029

Novel coumarin-based fluorescent probe for selective detection of Cu(II)

Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jan 5:152:18-22. doi: 10.1016/j.saa.2015.07.029. Epub 2015 Jul 7.

Authors

Ahmadreza Bekhradnia¹, Elham Domehri², Masome Khosravi²

Affiliations

¹ Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address: abekhradnia@gmail.com.
² Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran.

PMID: 26186393
DOI: 10.1016/j.saa.2015.07.029

Abstract

We report an efficient and convenient method for preparing nitro-3-carboxamide coumarin derivatives, proposed as novel fluorescent chemosensor, through microwave irradiation. This compound can be used as fluorescent probe for Cu(2+) with selectivity over other metal ions in aqueous solution. The fluorescence of 6-nitro-N-[2-(dimethylamino)ethyl]-2-oxo-2H-chromene-3-carboxamide(3) is the highest in the presence of Cu(2+), with stronger excitation at λ=320nm than for the other cations tested.

Keywords: Cation recognition; Coumarin derivatives; Fluorescent chemosensor.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cations, Divalent / analysis
Copper / analysis*
Coumarins / chemistry*
Fluorescence
Fluorescent Dyes / chemical synthesis
Fluorescent Dyes / chemistry*
Models, Molecular
Spectrometry, Fluorescence

Substances

Cations, Divalent
Coumarins
Fluorescent Dyes
Copper
coumarin