Candidate gene methylation studies are at high risk of erroneous conclusions

Epigenomics. 2015;7(1):13-5. doi: 10.2217/epi.14.70.

Authors

Andrey A Shabalin¹, Karolina A Aberg, Edwin J C G van den Oord

Affiliation

¹ Center for Biomarker Research & Personalized Medicine, Virginia Common-wealth University, PO Box 980533, Richmond, VA 23298, USA.

No abstract available

Keywords: DNA methylation; candidate gene study; false discoveries; methylome-wide association study; principal component analysis.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

DNA Methylation*
Genes
Genetic Association Studies*
Humans

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