Abstract
The Donryu rat strain is a commonly used model for endometrial cancer disease study. We sequenced this rat strain mitochondrial genome for the first time (GenBank Accession No. KM114605). Its mitogenome was 16,307 bp and coding 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes. A total of 96 SNPs were examined when compared to reference BN sequence.
Keywords:
Endometrial cancer; genome; mitochondrion.
MeSH terms
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Animals
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Codon
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DNA, Mitochondrial / chemistry
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DNA, Mitochondrial / isolation & purification
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DNA, Mitochondrial / metabolism
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Disease Models, Animal
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Endometrial Neoplasms / genetics*
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Endometrial Neoplasms / pathology
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Female
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Genome, Mitochondrial*
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Open Reading Frames / genetics
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Polymorphism, Single Nucleotide
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RNA, Ribosomal / chemistry
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RNA, Ribosomal / isolation & purification
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RNA, Ribosomal / metabolism
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RNA, Transfer / chemistry
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RNA, Transfer / isolation & purification
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RNA, Transfer / metabolism
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Rats
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Rats, Inbred BN
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Sequence Analysis, DNA
Substances
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Codon
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DNA, Mitochondrial
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RNA, Ribosomal
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RNA, Transfer