Synthesis of dibenzopyranones through palladium-catalyzed directed C-H activation/carbonylation of 2-arylphenols

Shuang Luo; Fei-Xian Luo; Xi-Sha Zhang; Zhang-Jie Shi

doi:10.1002/anie.201304295

Synthesis of dibenzopyranones through palladium-catalyzed directed C-H activation/carbonylation of 2-arylphenols

Angew Chem Int Ed Engl. 2013 Sep 27;52(40):10598-601. doi: 10.1002/anie.201304295. Epub 2013 Aug 12.

Authors

Shuang Luo¹, Fei-Xian Luo, Xi-Sha Zhang, Zhang-Jie Shi

Affiliation

¹ Beijing National Laboratory of Molecular Sciences (BNLMS), PKU Green Chemistry Centre and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871 (China).

PMID: 23940082
DOI: 10.1002/anie.201304295

Abstract

Dibenzopyranones were synthesized by a palladium-catalyzed phenol-directed C-H activation/carbonylation of 2-phenylphenol derivatives in the presence of CO. Pd(OAc)2 was used as a catalyst and Cu(OAc)2 as a catalytic oxidant in the presence of air.

Keywords: C-H activation; carbonylation; dibenzopyranone; phenol; synthetic methods.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzopyrans / chemical synthesis*
Benzopyrans / chemistry
Catalysis
Molecular Structure
Palladium / chemistry*
Phenol / chemistry*
Protein Carbonylation
Stereoisomerism

Substances

Benzopyrans
Phenol
Palladium