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Pediatr Dev Pathol. 2013 Jul-Aug;16(4):308-11. doi: 10.2350/13-01-1295-CR.1. Epub 2013 Mar 26.

Giant cell tumor of bone in a child with Goltz syndrome.

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  • 1Department of Pathology and Laboratory Medicine, Children's Mercy Hospital and Clinics, Kansas City, MO 64108, USA.


Giant cell tumor of bone is a neoplasm that is rarely seen in children. Goltz syndrome is a disorder that affects multiple ectodermal and mesodermal tissues and has occasionally been associated with giant cell tumors of bone. Our case of giant cell tumor in a 5-year-old girl with Goltz syndrome suggests that this syndrome provides a unique situation wherein the practitioner should consider giant cell tumor of bone, even in a pediatric setting.

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