Biocompatible, functional spheres based on oxidative coupling assembly of green tea polyphenols

J Am Chem Soc. 2013 Mar 20;135(11):4179-82. doi: 10.1021/ja311374b. Epub 2013 Mar 11.

Abstract

Green luminescent, monodisperse, smooth, porous and hollow spheres were simply prepared by Cu(2+) and temperature mediated oxidative coupling assembly of green tea polyphenols in water. These polymeric tea polyphenol spheres are GSH responsive, acid resistant but alkali-responsive, ideally used as platform for controlled delivery of functional guests.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibiotics, Antineoplastic / administration & dosage
  • Biocompatible Materials / chemical synthesis
  • Biocompatible Materials / chemistry*
  • Copper / chemistry
  • Delayed-Action Preparations / chemical synthesis
  • Delayed-Action Preparations / chemistry*
  • Doxorubicin / administration & dosage
  • Fluorescein-5-isothiocyanate / administration & dosage
  • Models, Molecular
  • Oxidation-Reduction
  • Polyphenols / chemical synthesis
  • Polyphenols / chemistry*
  • Porosity
  • Rhodamines / administration & dosage
  • Tea / chemistry*

Substances

  • Antibiotics, Antineoplastic
  • Biocompatible Materials
  • Delayed-Action Preparations
  • Polyphenols
  • Rhodamines
  • Tea
  • Copper
  • Doxorubicin
  • Fluorescein-5-isothiocyanate
  • rhodamine B