Common mechanisms of auditory hallucinations-perfusion studies in epilepsy

Martinus Hauf; Roland Wiest; Kaspar Schindler; Kay Jann; Thomas Dierks; Werner Strik; Gerhard Schroth; Daniela Hubl

doi:10.1016/j.pscychresns.2012.06.007

Common mechanisms of auditory hallucinations-perfusion studies in epilepsy

Psychiatry Res. 2013 Mar 30;211(3):268-70. doi: 10.1016/j.pscychresns.2012.06.007. Epub 2012 Nov 13.

Authors

Martinus Hauf¹, Roland Wiest, Kaspar Schindler, Kay Jann, Thomas Dierks, Werner Strik, Gerhard Schroth, Daniela Hubl

Affiliation

¹ Institute for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, and University of Bern, Switzerland.

PMID: 23154091
DOI: 10.1016/j.pscychresns.2012.06.007

Abstract

Auditory hallucinations (AH) occur in various neurological and psychiatric disorders. In psychosis, increased neuronal activity in the primary auditory cortex (PAC) contributes to AH. We investigated functional neuroanatomy of epileptic hallucinations by measuring cerebral perfusion in three patients with AH during simple partial status epilepticus. Hyperperfusion in the temporal lobe covering the PAC occurred in all patients. Our perfusion data support the hypothesis of PAC being a constituting element in the genesis of AH independent of their aetiology.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Brain Mapping
Cerebrovascular Circulation*
Electroencephalography
Epilepsy / complications*
Female
Hallucinations / etiology*
Humans
Middle Aged
Perfusion Imaging*
Retrospective Studies
Spin Labels
Temporal Lobe / physiopathology*

Substances

Spin Labels