Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis

Angew Chem Int Ed Engl. 2011 Mar 21;50(13):2951-3. doi: 10.1002/anie.201007896. Epub 2011 Feb 25.
No abstract available

MeSH terms

  • Biocatalysis
  • Models, Molecular
  • Molecular Structure
  • Mutagenesis, Site-Directed
  • Oxidoreductases / chemistry
  • Oxidoreductases / genetics*
  • Oxidoreductases / metabolism
  • Stereoisomerism
  • Tryptophan / analogs & derivatives
  • Tryptophan / chemical synthesis
  • Tryptophan / chemistry

Substances

  • 7-chlorotryptophan
  • Tryptophan
  • Oxidoreductases
  • tryptophan halogenase