PEGylation of carboxylic acid-functionalized germanium nanowires

Vincent C Holmberg; Michael R Rasch; Brian A Korgel

doi:10.1021/la102124y

PEGylation of carboxylic acid-functionalized germanium nanowires

Langmuir. 2010 Sep 7;26(17):14241-6. doi: 10.1021/la102124y.

Authors

Vincent C Holmberg¹, Michael R Rasch, Brian A Korgel

Affiliation

¹ Department of Chemical Engineering, Texas Materials Institute, and Center for Nano- and Molecular Science and Technology, The University of Texas at Austin, Austin, Texas 78712-1062, USA.

PMID: 20698505
DOI: 10.1021/la102124y

Abstract

Germanium (Ge) nanowires were produced in solution by supercritical fluid-liquid-solid (SFLS) growth and then functionalized with carboxylic acid groups by in situ thermal thiolation with mercaptoundecanoic acid. Polyethylene glycol (PEG) was grafted to the carboxylic acid-terminated Ge nanowires using carbodiimide coupling chemistry. The nanowires were characterized using attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy and transmission electron microscopy (TEM) to confirm the surface modification of the nanowires. Dispersions of PEGylated Ge nanowires in dimethylsulfoxide (DMSO) were stable for days. The PEGylated Ge nanowires were also dispersible in aqueous solution over a wide range of pH and ionic strength.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Carboxylic Acids / chemistry*
Germanium / chemistry*
Nanowires / chemistry*
Particle Size
Polyethylene Glycols / chemistry*
Surface Properties

Substances

Carboxylic Acids
Germanium
Polyethylene Glycols

Grants and funding

R01 CA132032/CA/NCI NIH HHS/United States