High-molecular-weight polyquinoxaline-based helically chiral phosphine (PQXphos) as chirality-switchable, reusable, and highly enantioselective monodentate ligand in catalytic asymmetric hydrosilylation of styrenes

Takeshi Yamamoto; Tetsuya Yamada; Yuuya Nagata; Michinori Suginome

doi:10.1021/ja102428q

High-molecular-weight polyquinoxaline-based helically chiral phosphine (PQXphos) as chirality-switchable, reusable, and highly enantioselective monodentate ligand in catalytic asymmetric hydrosilylation of styrenes

J Am Chem Soc. 2010 Jun 16;132(23):7899-901. doi: 10.1021/ja102428q.

Authors

Takeshi Yamamoto¹, Tetsuya Yamada, Yuuya Nagata, Michinori Suginome

Affiliation

¹ Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 20481636
DOI: 10.1021/ja102428q

Abstract

A polyquinoxaline-based helical polymer ligand bearing both helical-sense-determining chiral side chains and coordinating diarylphosphino side chains exhibits solvent-dependent formation of P- or M-helical structures, with which either the S- or R-hydrosilylation product was obtained with high (>93% enantiomeric excess) enantioselectivities.