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Year Number of Results
2008 1
2009 3
2010 5
2011 7
2012 7
2013 8
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2015 3
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2017 2
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2020 2
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2023 4
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Page 1
2009 pandemic H1N1 influenza virus replicates in human lung tissues.
Zhang J, Zhang Z, Fan X, Liu Y, Wang J, Zheng Z, Chen R, Wang P, Song W, Chen H, Guan Y. Zhang J, et al. J Infect Dis. 2010 May 15;201(10):1522-6. doi: 10.1086/650544. J Infect Dis. 2010. PMID: 20370480 Free PMC article.
The replication activity of 2009 pandemic H1N1 influenza virus in human lung cells was evaluated in this study. Twenty-two surgically removed human lung tissue samples were infected ex vivo with pande …
The replication activity of 2009 pandemic H1N1 influenza virus in human lung cells w …
Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants.
Ferrando VA, Friedrich ME, Gandhi S, Mellmann A, Masemann D, Christersson A, Anhlan D, Brunotte L, Stoll M, Harder T, Beer M, Boergeling Y, Ludwig S. Ferrando VA, et al. Emerg Microbes Infect. 2023 Dec;12(1):2212809. doi: 10.1080/22221751.2023.2212809. Emerg Microbes Infect. 2023. PMID: 37191590 Free PMC article.
Influenza A viruses (IAV) cause annual epidemics and occasional pandemics in humans. The most recent pandemic outbreak occurred in 2009 with H1N1pdm09. This virus, which most likely reassorted in swine before its transmission to humans …
Influenza A viruses (IAV) cause annual epidemics and occasional pandemics in humans. The most recent pandemic ou …
Influenza A viruses target type II pneumocytes in the human lung.
Weinheimer VK, Becher A, Tönnies M, Holland G, Knepper J, Bauer TT, Schneider P, Neudecker J, Rückert JC, Szymanski K, Temmesfeld-Wollbrueck B, Gruber AD, Bannert N, Suttorp N, Hippenstiel S, Wolff T, Hocke AC. Weinheimer VK, et al. J Infect Dis. 2012 Dec 1;206(11):1685-94. doi: 10.1093/infdis/jis455. Epub 2012 Jul 24. J Infect Dis. 2012. PMID: 22829640 Free PMC article.
However, it is unknown whether this cellular tropism contributes to high viral virulence because the primary target cells of other influenza viruses have not been systematically studied. METHODS: We provide the first comparison of the replication, tropism, and cytok …
However, it is unknown whether this cellular tropism contributes to high viral virulence because the primary target cells of other influe …
Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung.
Wu W, Zhang W, Booth JL, Metcalf JP. Wu W, et al. PLoS One. 2012;7(11):e49856. doi: 10.1371/journal.pone.0049856. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185463 Free PMC article.
Exposure of human lung tissue to either pandemic or seasonal influenza virus resulted in infection and replication in alveolar epithelial cells. Pandemic virus induces a diminished RIG-I mRNA and antiviral cytokine re …
Exposure of human lung tissue to either pandemic or seasonal influenza virus resulted in infection …
Pandemic 2009 H1N1 influenza virus is resistant to the antiviral activity of several interferon alpha subtypes.
Scagnolari C, Trombetti S, Soldà A, Selvaggi C, Monteleone K, Spano L, Pierangeli A, Clementi M, Turriziani O, Antonelli G. Scagnolari C, et al. J Interferon Cytokine Res. 2011 Jun;31(6):475-9. doi: 10.1089/jir.2010.0125. Epub 2011 Jan 15. J Interferon Cytokine Res. 2011. PMID: 21235413
Interferons (IFNs) are critically important in the control of influenza A virus infections. To better understand the pathogenic characteristics of the pandemic 2009 H1N1 influenza virus (pH1N1) from an innate immunity viewpoint, we …
Interferons (IFNs) are critically important in the control of influenza A virus infections. To better understand the pathogeni …
Pandemic 2009 H1N1 influenza virus causes diffuse alveolar damage in cynomolgus macaques.
Herfst S, van den Brand JM, Schrauwen EJ, de Wit E, Munster VJ, van Amerongen G, Linster M, Zaaraoui F, van Ijcken WF, Rimmelzwaan GF, Osterhaus AD, Fouchier RA, Andeweg AC, Kuiken T. Herfst S, et al. Vet Pathol. 2010 Nov;47(6):1040-7. doi: 10.1177/0300985810374836. Epub 2010 Jul 20. Vet Pathol. 2010. PMID: 20647595
The pathogenesis of lower respiratory tract disease from the pandemic 2009 H1N1 (H1N1v) influenza A virus is poorly understood. Therefore, either H1N1v virus or a seasonal human H1N1 influenza A virus was inocu …
The pathogenesis of lower respiratory tract disease from the pandemic 2009 H1N1 (H1N1v) influenza A virus …
The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice.
Chen Y, Bai T, Zhu W, Gao R, Deng Z, Shi Y, Zou S, Huang Y, Li X, Li F, Feng Z, Chen T, Yang J, Wang D, Gao L, Shu Y. Chen Y, et al. Sci China Life Sci. 2018 Jul;61(7):836-843. doi: 10.1007/s11427-017-9156-1. Epub 2018 Feb 10. Sci China Life Sci. 2018. PMID: 29445999
Human influenza viruses preferentially bind to sialic acid-alpha2,6-galactose (SAalpha2,6Gal) receptors, which are predominant in human upper respiratory epithelia, whereas avian influenza viruses preferentially bind to SAalpha2,3Gal receptors. ...In t …
Human influenza viruses preferentially bind to sialic acid-alpha2,6-galactose (SAalpha2,6Gal) receptors, which are predominant …
Cytokine and chemokine profiles in lung tissues from fatal cases of 2009 pandemic influenza A (H1N1): role of the host immune response in pathogenesis.
Gao R, Bhatnagar J, Blau DM, Greer P, Rollin DC, Denison AM, Deleon-Carnes M, Shieh WJ, Sambhara S, Tumpey TM, Patel M, Liu L, Paddock C, Drew C, Shu Y, Katz JM, Zaki SR. Gao R, et al. Am J Pathol. 2013 Oct;183(4):1258-1268. doi: 10.1016/j.ajpath.2013.06.023. Epub 2013 Aug 11. Am J Pathol. 2013. PMID: 23938324 Free PMC article.
Pathological studies on fatal cases caused by 2009 pandemic influenza H1N1 virus (2009 pH1N1) reported extensive diffuse alveolar damage and virus infection predominantly in the lung parenchyma. ...FasL and caspase-3 are inv …
Pathological studies on fatal cases caused by 2009 pandemic influenza H1N1 virus (2009 pH1N1) repo …
Antiviral potential of exogenous human omega interferon to inhibit pandemic 2009 A (H1N1) influenza virus.
Xu C, Song X, Fu L, Dong D, Wu S, Li G, Yi S, Yu T, Yu R, Hou L, Chen W. Xu C, et al. Viral Immunol. 2011 Oct;24(5):369-74. doi: 10.1089/vim.2011.0003. Viral Immunol. 2011. PMID: 22004136
The pandemic 2009 H1N1 influenza virus broke out in North America and spread rapidly throughout the world. ...With daily intranasal treatment with human IFN-omega the viral load of pandemic 2009 A (H1N1) influenza …
The pandemic 2009 H1N1 influenza virus broke out in North America and spread rapidly throughout the world …
Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model.
Nieto A, Vasilijevic J, Santos NB, Zamarreño N, López P, Amorim MJ, Falcon A. Nieto A, et al. Front Immunol. 2019 Feb 6;10:132. doi: 10.3389/fimmu.2019.00132. eCollection 2019. Front Immunol. 2019. PMID: 30787926 Free PMC article.
Characterization of a pandemic 2009 H1N1 influenza virus isolated from a fatal case patient (F-IAV), showed the presence of three different mutations; potential determinants of its high pathogenicity that were located in the polymerase subunits …
Characterization of a pandemic 2009 H1N1 influenza virus isolated from a fatal case patient (F-IAV), show …
47 results