Optically active dinuclear palladium complexes containing a Pd-Pd bond: preparation and enantioinduction ability in asymmetric ring-opening reactions

Tomokazu Ogura; Kazuhiro Yoshida; Akira Yanagisawa; Tsuneo Imamoto

doi:10.1021/ol900533h

Optically active dinuclear palladium complexes containing a Pd-Pd bond: preparation and enantioinduction ability in asymmetric ring-opening reactions

Org Lett. 2009 Jun 4;11(11):2245-8. doi: 10.1021/ol900533h.

Authors

Tomokazu Ogura¹, Kazuhiro Yoshida, Akira Yanagisawa, Tsuneo Imamoto

Affiliation

¹ Department of Chemistry, Graduate School of Science, Chiba University, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.

PMID: 19413329
DOI: 10.1021/ol900533h

Abstract

Optically active dinuclear palladium complexes containing a Pd-Pd bond were prepared by using (R,R)-bis(tert-butylmethylphosphino)methane ((R,R)-t-Bu-MiniPHOS). The dinuclear palladium complexes coupled with silver triflate exhibited good to excellent enantioselectivities up to 99% in palladium-catalyzed alkylative ring-opening reactions of azabenzonorbornadienes.