Intermolecular radical addition of alkylthio- and arylthiodiphenylphosphines to terminal alkynes

Tatsuya Wada; Azusa Kondoh; Hideki Yorimitsu; Koichiro Oshima

doi:10.1021/ol800059n

Intermolecular radical addition of alkylthio- and arylthiodiphenylphosphines to terminal alkynes

Org Lett. 2008 Mar 20;10(6):1155-7. doi: 10.1021/ol800059n. Epub 2008 Feb 28.

Authors

Tatsuya Wada¹, Azusa Kondoh, Hideki Yorimitsu, Koichiro Oshima

Affiliation

¹ Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 18303899
DOI: 10.1021/ol800059n

Abstract

Intermolecular radical thiophosphination of terminal alkynes with alkylthio- and arylthiophosphines affords 1-thio-2-phosphino-1-alkenes in good yields. The addition reaction proceeds predominantly in an anti fashion to yield E isomers.