Chemical composition and anti-inflammatory activity of the volatile fractions from the bark of eight Mexican Bursera species

Planta Med. 2005 Sep;71(9):825-8. doi: 10.1055/s-2005-871293.

Abstract

The volatile fractions from the bark of eight species of Mexican Bursera were obtained using steam distillation and were subjected to tandem GC-MS analysis for identification of the main constituents. The most abundant components of steam volatiles were monoterpenoids from which alpha-terpineol, terpinen-4-ol, alpha-thujene, linalool and limonene were most frequently isolated. A series of sesquiterpenes and long-chain hydrocarbons were isolated and identified from the barks of some of the studied species . Some volatiles were assayed for anti-inflammatory activity using the TPA-induced ear edema bioassay in mice. The volatile fraction from Bursera lancifolia was about half as active as indomethacin.

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Bursera*
  • Edema / chemically induced
  • Edema / prevention & control*
  • Gas Chromatography-Mass Spectrometry
  • Male
  • Medicine, Traditional
  • Mexico
  • Mice
  • Mice, Inbred Strains
  • Monoterpenes / administration & dosage
  • Monoterpenes / chemistry
  • Monoterpenes / pharmacology
  • Monoterpenes / therapeutic use
  • Oils, Volatile / administration & dosage
  • Oils, Volatile / chemistry
  • Oils, Volatile / pharmacology
  • Oils, Volatile / therapeutic use
  • Phytotherapy*
  • Plant Bark
  • Plant Oils / administration & dosage
  • Plant Oils / chemistry
  • Plant Oils / pharmacology*
  • Plant Oils / therapeutic use
  • Tetradecanoylphorbol Acetate

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Monoterpenes
  • Oils, Volatile
  • Plant Oils
  • Tetradecanoylphorbol Acetate