Congenital misalignment of pulmonary veins with alveolar capillary dysplasia causing persistent neonatal pulmonary hypertension: report of two affected siblings

C Gutierrez; A Rodriguez; S Palenzuela; C Forteza; J L Rossello

doi:10.1007/s100249910035

Congenital misalignment of pulmonary veins with alveolar capillary dysplasia causing persistent neonatal pulmonary hypertension: report of two affected siblings

Pediatr Dev Pathol. 2000 May-Jun;3(3):271-6. doi: 10.1007/s100249910035.

Authors

C Gutierrez¹, A Rodriguez, S Palenzuela, C Forteza, J L Rossello

Affiliation

¹ Pediatric Pathology Laboratory, Hospital Pereira Rossell, Boulevard Artigas 1550, Casilla de Correo 16059, Montevideo, Uruguay,

PMID: 10742415
DOI: 10.1007/s100249910035

Abstract

Misalignment of pulmonary vessels with alveolar capillary dysplasia is a rare cause of persistent pulmonary hypertension of the newborn. Most of the reported cases have been sporadic. We present two consecutive affected siblings with this disorder. This is the fifth reported family occurrence of this condition. In addition to the pulmonary abnormality, one of our cases had duodenal atresia.

Publication types

Case Reports

MeSH terms

Arteriovenous Malformations / pathology*
Bronchi / blood supply
Capillaries / abnormalities
Fatal Outcome
Female
Humans
Infant, Newborn
Lung / blood supply*
Lung / pathology
Nuclear Family
Persistent Fetal Circulation Syndrome / etiology
Persistent Fetal Circulation Syndrome / pathology*
Pulmonary Alveoli / blood supply
Pulmonary Artery / abnormalities*
Pulmonary Veins / abnormalities*