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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1985 1
1987 2
1989 6
1990 2
1992 1
1993 9
1994 5
1995 3
1996 5
1997 4
1998 7
1999 5
2000 2
2001 4
2002 3
2003 12
2004 6
2005 7
2006 12
2007 7
2008 10
2009 3
2010 14
2011 8
2012 8
2013 6
2014 7
2015 9
2016 9
2017 11
2018 8
2019 16
2020 15
2021 15
2022 11
2023 15
2024 4

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250 results

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Page 1
The roles of microbial products in the development of colorectal cancer: a review.
Fang Y, Yan C, Zhao Q, Xu J, Liu Z, Gao J, Zhu H, Dai Z, Wang D, Tang D. Fang Y, et al. Bioengineered. 2021 Dec;12(1):720-735. doi: 10.1080/21655979.2021.1889109. Bioengineered. 2021. PMID: 33618627 Free PMC article. Review.
In this review, recent studies are examined in order to describe the contribution metabolites and toxicants which are produced by gut microbes make to CRC, primarily focusing on the involved molecular mechanisms.Abbreviations: CRC: colorectal cancer; SCFAs: short chain fatty acid …
In this review, recent studies are examined in order to describe the contribution metabolites and toxicants which are produced by gut microb …
Gut microbial metabolite butyrate improves anticancer therapy by regulating intracellular calcium homeostasis.
Che Y, Chen G, Guo Q, Duan Y, Feng H, Xia Q. Che Y, et al. Hepatology. 2023 Jul 1;78(1):88-102. doi: 10.1097/HEP.0000000000000047. Epub 2023 Jan 3. Hepatology. 2023. PMID: 36947402
Butyrate levels are lower in the plasma of HCC patients by gas chromatography-mass spectrometry (GC-MS) analysis. Butyrate supplementation or depletion of short-chain Acyl-CoA dehydrogenase (SCAD) gene (ACADS), encoding a key enzyme for butyrate metabo …
Butyrate levels are lower in the plasma of HCC patients by gas chromatography-mass spectrometry (GC-MS) analysis. Butyrate supplementation o …
Short-Chain Acyl-CoA Dehydrogenase Deficiency.
Wolfe L, Jethva R, Oglesbee D, Vockley J. Wolfe L, et al. 2011 Sep 22 [updated 2018 Aug 9]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2011 Sep 22 [updated 2018 Aug 9]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 21938826 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: Most infants with short-chain acyl-CoA dehydrogenase deficiency (SCADD) identified through newborn screening programs have remained well, and asymptomatic relatives who meet diagnostic criteria are reported. ...At conception, each sib of an …
CLINICAL CHARACTERISTICS: Most infants with short-chain acyl-CoA dehydrogenase deficiency (SCADD) identified through newborn s …
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2).
Sharma RS, Harrison DJ, Kisielewski D, Cassidy DM, McNeilly AD, Gallagher JR, Walsh SV, Honda T, McCrimmon RJ, Dinkova-Kostova AT, Ashford MLJ, Dillon JF, Hayes JD. Sharma RS, et al. Cell Mol Gastroenterol Hepatol. 2017 Dec 13;5(3):367-398. doi: 10.1016/j.jcmgh.2017.11.016. eCollection 2018 Mar. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29552625 Free PMC article.
Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets.
Di'Narzo AF, Houten SM, Kosoy R, Huang R, Vaz FM, Hou R, Wei G, Wang W, Comella PH, Dodatko T, Rogatsky E, Stojmirovic A, Brodmerkel C, Perrigoue J, Hart A, Curran M, Friedman JR, Zhu J, Agrawal M, Cho J, Ungaro R, Dubinsky MC, Sands BE, Suárez-Fariñas M, Schadt EE, Colombel JF, Kasarskis A, Hao K, Argmann C. Di'Narzo AF, et al. Gastroenterology. 2022 Mar;162(3):828-843.e11. doi: 10.1053/j.gastro.2021.11.015. Epub 2021 Nov 13. Gastroenterology. 2022. PMID: 34780722 Free PMC article.
Using this resource, we show that a novel metabolite quantitative trait locus for serum butyrate levels containing ACADS was not supported as causal for IBD; replicate the association of serum omega-6 containing lipids with the fatty acid desaturase 1/2 locus and identify …
Using this resource, we show that a novel metabolite quantitative trait locus for serum butyrate levels containing ACADS was not supp …
Short-chain acyl-CoA dehydrogenase deficiency: from gene to cell pathology and possible disease mechanisms.
Nochi Z, Olsen RKJ, Gregersen N. Nochi Z, et al. J Inherit Metab Dis. 2017 Sep;40(5):641-655. doi: 10.1007/s10545-017-0047-1. Epub 2017 May 17. J Inherit Metab Dis. 2017. PMID: 28516284 Review.
Short-chain acyl-CoA dehydrogenase deficiency (SCADD) is an inherited disorder of mitochondrial fatty acid oxidation that is characterized by the presence of increased butyrylcarnitine and ethylmalonic acid (EMA) concentrations in plasma and urine. ...Accordingly, t …
Short-chain acyl-CoA dehydrogenase deficiency (SCADD) is an inherited disorder of mitochondrial fatty acid oxidation that is c …
IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria.
Gadbery JE, Round JW, Yuan T, Wipperman MF, Story KT, Crowe AM, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS. Gadbery JE, et al. Biochemistry. 2020 Mar 17;59(10):1113-1123. doi: 10.1021/acs.biochem.0c00005. Epub 2020 Mar 4. Biochemistry. 2020. PMID: 32101684 Free PMC article.
Steroid-degrading bacteria, including Mycobacterium tuberculosis (Mtb), utilize an architecturally distinct subfamily of acyl coenzyme A dehydrogenases (ACADs) for steroid catabolism. These ACADs are alpha(2)beta(2) heterotetramers that are usually encoded by adjace …
Steroid-degrading bacteria, including Mycobacterium tuberculosis (Mtb), utilize an architecturally distinct subfamily of acyl coenzyme A deh …
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Zhong X, Li Z, Xu Q, Peng H, Su Y, Le K, Shu Z, Liao Y, Ma Z, Pan X, Xu S, Zhou S. Zhong X, et al. J Hypertens. 2023 May 1;41(5):775-793. doi: 10.1097/HJH.0000000000003399. Epub 2023 Mar 1. J Hypertens. 2023. PMID: 36883465
OBJECTIVES: Short-chain acyl-CoA dehydrogenase (SCAD), a key enzyme in the fatty acid oxidation process, is not only involved in ATP synthesis but also regulates the production of mitochondrial reactive oxygen species (ROS) and nitric oxide synthesis. ...S …
OBJECTIVES: Short-chain acyl-CoA dehydrogenase (SCAD), a key enzyme in the fatty acid oxidation process, is not only in …
Novel and Recurrent ACADS Mutations and Clinical Manifestations Observed in Korean Patients with Short-chain Acyl-coenzyme a Dehydrogenase Deficiency.
Kim YM, Cheon CK, Park KH, Park S, Kim GH, Yoo HW, Lee KA, Ko JM. Kim YM, et al. Ann Clin Lab Sci. 2016 Jul;46(4):360-6. Ann Clin Lab Sci. 2016. PMID: 27466294
Short-chain acyl-CoA dehydrogenase (SCAD) catalyzes the first step in mitochondrial short-chain beta-oxidation, and its deficiency is caused by mutations in the ACADS We sought to investigate the spectrum ACADS mutations and associated clinical …
Short-chain acyl-CoA dehydrogenase (SCAD) catalyzes the first step in mitochondrial short-chain beta-oxidation, and its …
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Peng H, Xie M, Zhong X, Su Y, Qin X, Xu Q, Zhou S. Peng H, et al. Eur J Pharmacol. 2023 Sep 5;954:175849. doi: 10.1016/j.ejphar.2023.175849. Epub 2023 Jun 16. Eur J Pharmacol. 2023. PMID: 37331684
Short-chain acyl-CoA dehydrogenase (SCAD), the rate-limiting enzyme for fatty acid beta-oxidation, has a negative regulatory effect on pathological cardiac hypertrophy and fibrosis. ...Insufficient riboflavin intake can lead to symptoms similar to short-chain …
Short-chain acyl-CoA dehydrogenase (SCAD), the rate-limiting enzyme for fatty acid beta-oxidation, has a negative regul …
250 results