Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 2
1982 1
1983 1
1984 4
1985 2
1986 4
1987 2
1988 3
1989 10
1990 14
1991 22
1992 34
1993 40
1994 46
1995 43
1996 48
1997 44
1998 62
1999 37
2000 32
2001 48
2002 68
2003 63
2004 67
2005 71
2006 87
2007 88
2008 112
2009 148
2010 143
2011 184
2012 227
2013 248
2014 251
2015 272
2016 265
2017 246
2018 269
2019 263
2020 276
2021 217
2022 132
2023 139
2024 52

Text availability

Article attribute

Article type

Publication date

Search Results

3,868 results

Results by year

Filters applied: . Clear all
Page 1
Structural variants drive context-dependent oncogene activation in cancer.
Xu Z, Lee DS, Chandran S, Le VT, Bump R, Yasis J, Dallarda S, Marcotte S, Clock B, Haghani N, Cho CY, Akdemir KC, Tyndale S, Futreal PA, McVicker G, Wahl GM, Dixon JR. Xu Z, et al. Nature. 2022 Dec;612(7940):564-572. doi: 10.1038/s41586-022-05504-4. Epub 2022 Dec 7. Nature. 2022. PMID: 36477537 Free PMC article.
However, only a small minority of SVs are associated with altered gene expression(4,5), and it remains unclear why certain SVs lead to changes in distal gene expression and others do not. ...However, activity-by-contact models are only predictive of specific subsets …
However, only a small minority of SVs are associated with altered gene expression(4,5), and it remains unclear why certain SVs lead t …
Oncogenes and tumor suppressor genes.
Lee EY, Muller WJ. Lee EY, et al. Cold Spring Harb Perspect Biol. 2010 Oct;2(10):a003236. doi: 10.1101/cshperspect.a003236. Epub 2010 Aug 18. Cold Spring Harb Perspect Biol. 2010. PMID: 20719876 Free PMC article. Review.
Breast cancer progression involves multiple genetic events, which can activate dominant-acting oncogenes and disrupt the function of specific tumor suppressor genes. This article describes several key oncogene and tumor suppressor signaling networks that have been implicat …
Breast cancer progression involves multiple genetic events, which can activate dominant-acting oncogenes and disrupt the function of specifi …
Mantle-cell lymphoma.
Campo E, Raffeld M, Jaffe ES. Campo E, et al. Semin Hematol. 1999 Apr;36(2):115-27. Semin Hematol. 1999. PMID: 10319380 Review.
These cases have a higher proliferative activity and a more aggressive clinical evolution. MCL is genetically characterized by 11q13 translocations and bcl-1 rearrangement. This alteration leads to a constant overexpression of cyclin D1, which plays an important pat …
These cases have a higher proliferative activity and a more aggressive clinical evolution. MCL is genetically characterized by 11q13 translo …
Cyclin D and oncogenesis.
Motokura T, Arnold A. Motokura T, et al. Curr Opin Genet Dev. 1993 Feb;3(1):5-10. doi: 10.1016/s0959-437x(05)80334-x. Curr Opin Genet Dev. 1993. PMID: 8453274 Review.
The D-type cyclins are among the candidate 'G1 cyclins' in higher eukaryotes that may regulate G1-S-phase progression. The human cyclin D1 gene, also known as PRAD1 (and previously as D11S287), is a putative proto-oncogene strongly implicated in several types of hum …
The D-type cyclins are among the candidate 'G1 cyclins' in higher eukaryotes that may regulate G1-S-phase progression. The human cyclin D1 …
Double-hit B-cell lymphomas.
Aukema SM, Siebert R, Schuuring E, van Imhoff GW, Kluin-Nelemans HC, Boerma EJ, Kluin PM. Aukema SM, et al. Blood. 2011 Feb 24;117(8):2319-31. doi: 10.1182/blood-2010-09-297879. Epub 2010 Nov 30. Blood. 2011. PMID: 21119107 Free article. Review.
In this review we explore the existing literature for the most recurrent types of DH B-cell lymphomas and the involved genes with their functions, as well as their pathology and clinical aspects including therapy and prognosis. ...Compared to these DH lymphomas, BCL6(+)/MY …
In this review we explore the existing literature for the most recurrent types of DH B-cell lymphomas and the involved genes with the …
PRAD1/Cyclin D1 gene overexpression in mantle cell lymphoma.
Oka K, Ohno T, Yamaguchi M, Mahmud N, Miwa H, Kita K, Shiku H, Shirakawa S. Oka K, et al. Leuk Lymphoma. 1996 Mar;21(1-2):37-42. doi: 10.3109/10428199609067577. Leuk Lymphoma. 1996. PMID: 8907267 Review.
This translocation activates the PRAD1/cyclin D1 gene that is considered to be the Bcl-1 oncogene. PRAD1/cyclin D1 gene overexpression is closely associated with MCL. ...
This translocation activates the PRAD1/cyclin D1 gene that is considered to be the Bcl-1 oncogene. PRAD1/ …
Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation.
Uchimaru K, Endo K, Fujinuma H, Zukerberg L, Arnold A, Motokura T. Uchimaru K, et al. Jpn J Cancer Res. 1996 May;87(5):459-65. doi: 10.1111/j.1349-7006.1996.tb00246.x. Jpn J Cancer Res. 1996. PMID: 8641982 Free PMC article.
Cyclin D1 is one of the key regulators in G1 progression in the cell cycle and is also a candidate oncogene (termed PRAD1 or bcl-1) in several types of human tumors. We report a collaboration of the cyclin D1 gene with ras and a mutated form of p53 (p5 …
Cyclin D1 is one of the key regulators in G1 progression in the cell cycle and is also a candidate oncogene (termed PRAD1 or bcl …
Cyclin D1 (PRAD1, CCND1) and glutathione-S-transferase pi gene expression in head and neck squamous cell carcinoma.
Gaffey MJ, Iezzoni JC, Meredith SD, Boyd JC, Stoler MH, Weiss LM, Zukerberg LR, Levine PA, Arnold A, Williams ME. Gaffey MJ, et al. Hum Pathol. 1995 Nov;26(11):1221-6. doi: 10.1016/0046-8177(95)90197-3. Hum Pathol. 1995. PMID: 7590696
This region contains several putative oncogenes, including cyclin D1 (PRAD1, CCND1), which encodes for an important cell cycle regulatory protein, and the locus encoding for the drug-detoxifying enzyme glutathione-S-transferase-pi (GST-pi). To determine the relation …
This region contains several putative oncogenes, including cyclin D1 (PRAD1, CCND1), which encodes for an important cell cycle …
PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.
Rosenberg CL, Wong E, Petty EM, Bale AE, Tsujimoto Y, Harris NL, Arnold A. Rosenberg CL, et al. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9638-42. doi: 10.1073/pnas.88.21.9638. Proc Natl Acad Sci U S A. 1991. PMID: 1682919 Free PMC article.
Three of the seven centrocytic lymphomas had detectable BCL1 DNA rearrangement. Also, two unusual cases of CLL with BCL1 rearrangement overexpressed PRAD1, in contrast to five CLL controls. Thus, PRAD1 is an excellent candidate "BCL1 oncogene." …
Three of the seven centrocytic lymphomas had detectable BCL1 DNA rearrangement. Also, two unusual cases of CLL with BCL1 rearr …
3,868 results