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Page 1
Halofantrine.
[No authors listed] [No authors listed] 2021 Apr 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Apr 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000758 Free Books & Documents. Review.
Because no information is available on the use of halofantrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1]...
Because no information is available on the use of halofantrine during breastfeeding, an alternate drug may be preferred, especially w …
Halofantrine.
[No authors listed] [No authors listed] East Afr Med J. 1989 Dec;66(12):785-6. East Afr Med J. 1989. PMID: 2693066 Clinical Trial. No abstract available.
Halofantrine sensitivity.
Wildling E, Winkler S, Brandts C, Jenne L, Graninger W, Wernsdorfer WH, Bienzle U, Kremsner PG. Wildling E, et al. Lancet. 1993 Jul 3;342(8862):55-6. doi: 10.1016/0140-6736(93)91922-9. Lancet. 1993. PMID: 8100329 Clinical Trial. No abstract available.
Food-drug interactions.
Schmidt LE, Dalhoff K. Schmidt LE, et al. Drugs. 2002;62(10):1481-502. doi: 10.2165/00003495-200262100-00005. Drugs. 2002. PMID: 12093316 Review.
For other drugs, concomitant food intake may result in an increase in drug bioavailability either because of a food-induced increase in drug solubility (albendazole, atovaquone, griseofulvin, isotretinoin, lovastatin, mefloquine, saquinavir and tacrolimus) or because of the secre …
For other drugs, concomitant food intake may result in an increase in drug bioavailability either because of a food-induced increase in drug …
Antiparasitic agents.
Rosenblatt JE. Rosenblatt JE. Mayo Clin Proc. 1999 Nov;74(11):1161-75. doi: 10.4065/74.11.1161. Mayo Clin Proc. 1999. PMID: 10560606 Review.
Several newer agents have appeared in response to the development of multidrug resistant Plasmodium falciparum, especially in Southeast Asia. Halofantrine is available for the treatment of mild to moderate malaria due to P. falciparum and for P. vivax infections. Because o …
Several newer agents have appeared in response to the development of multidrug resistant Plasmodium falciparum, especially in Southeast Asia …
Clinical pharmacokinetics of halofantrine.
Karbwang J, Na Bangchang K. Karbwang J, et al. Clin Pharmacokinet. 1994 Aug;27(2):104-19. doi: 10.2165/00003088-199427020-00003. Clin Pharmacokinet. 1994. PMID: 7955774 Review.
The terminal elimination half-life is 5 days in patients with malaria. Halofantrine is biotransformed in the liver to its major metabolite N-debutyl-halofantrine. Plasma concentrations of this metabolite are observed soon after administration of halofantrine, …
The terminal elimination half-life is 5 days in patients with malaria. Halofantrine is biotransformed in the liver to its major metab …
Mechanism of cardiotoxicity of halofantrine.
Wesche DL, Schuster BG, Wang WX, Woosley RL. Wesche DL, et al. Clin Pharmacol Ther. 2000 May;67(5):521-9. doi: 10.1067/mcp.2000.106127. Clin Pharmacol Ther. 2000. PMID: 10824631 Review.
Because halofantrine was associated with electrocardiographic prolongation of the QT interval and ventricular arrhythmias, in vitro cardiac electrophysiologic studies (isolated perfused cardiac model and isolated ventricular myocytes) were conducted to test the hypothesis …
Because halofantrine was associated with electrocardiographic prolongation of the QT interval and ventricular arrhythmias, in vitro c …
Halofantrine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic potential.
Bryson HM, Goa KL. Bryson HM, et al. Drugs. 1992 Feb;43(2):236-58. doi: 10.2165/00003495-199243020-00009. Drugs. 1992. PMID: 1372221 Review.
Data concerning halofantrine in the treatment of P. ovale and P. malariae infections are still limited. ...The development of parasite resistance to halofantrine, like other blood schizontocides, is inevitable. Poor absorption resulting in variable peak plasma ha …
Data concerning halofantrine in the treatment of P. ovale and P. malariae infections are still limited. ...The development of parasit …
Resistance to Antimalarial Monotherapy Is Cyclic.
Weitzman R, Calfon-Peretz O, Saha T, Bloch N, Ben Zaken K, Rosenfeld A, Amitay M, Samson AO. Weitzman R, et al. J Clin Med. 2022 Jan 31;11(3):781. doi: 10.3390/jcm11030781. J Clin Med. 2022. PMID: 35160232 Free PMC article.
The antimalarial drugs that exhibit cyclic resistance are quinine, chloroquine, mefloquine, amodiaquine, artesunate, artemether, sulfadoxine, doxycycline, halofantrine, piperaquine, pyrimethamine, atovaquone, artemisinin, and dihydroartemisinin. ...
The antimalarial drugs that exhibit cyclic resistance are quinine, chloroquine, mefloquine, amodiaquine, artesunate, artemether, sulfadoxine …
Physical Characterization of Halofantrine-Encapsulated Fat Nanoemulsions.
Haidar I, Harding IH, Bowater IC, McDowall AW. Haidar I, et al. J Pharm Sci. 2019 Jun;108(6):2153-2161. doi: 10.1016/j.xphs.2019.01.021. Epub 2019 Jan 29. J Pharm Sci. 2019. PMID: 30703385
We report the colloidal characterization of halofantrine (Hf)-laden soybean oil fat emulsions. Hf increased the zeta potential, at all pH values, of the fat emulsions. ...
We report the colloidal characterization of halofantrine (Hf)-laden soybean oil fat emulsions. Hf increased the zeta potential, at al …
619 results