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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1989 2
1991 1
1992 1
1993 3
1994 1
1997 2
1998 4
1999 4
2000 3
2001 10
2002 9
2003 4
2004 7
2005 4
2006 9
2007 5
2008 11
2009 9
2010 6
2011 9
2012 15
2013 7
2014 12
2015 26
2016 19
2017 23
2018 25
2019 18
2020 17
2021 36
2022 29
2023 37
2024 12

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340 results

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Page 1
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Liu X, et al. Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10. Br J Sports Med. 2018. PMID: 29018060 Review.
Another six (undenatured type II collagen, avocado soybean unsaponifiables, methylsulfonylmethane, diacerein, glucosamine and chondroitin) revealed statistically significant improvements on pain, but were of unclear clinical importance. ...There were no differences between …
Another six (undenatured type II collagen, avocado soybean unsaponifiables, methylsulfonylmethane, diacerein, glucosamine and chondro …
Retraction.
[No authors listed] [No authors listed] Arthritis Rheumatol. 2023 Aug;75(8):1497. doi: 10.1002/art.42546. Epub 2023 Jun 20. Arthritis Rheumatol. 2023. PMID: 37337725
., Bohmova, J. and Rovensky, J. (2007), The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: A randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treat …
., Bohmova, J. and Rovensky, J. (2007), The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: …
Current Treatment Options for Osteoarthritis.
Hermann W, Lambova S, Muller-Ladner U. Hermann W, et al. Curr Rheumatol Rev. 2018;14(2):108-116. doi: 10.2174/1573397113666170829155149. Curr Rheumatol Rev. 2018. PMID: 28875826 Review.
The standard pharmacological treatment includes agents for control of pain and inflammation (non-steroidal anti-inflammatory drugs, analgesics including opioids, intraarticular corticosteroids) and the group of the symptomatic slow acting drugs for OA such as glucosamine sulfate, …
The standard pharmacological treatment includes agents for control of pain and inflammation (non-steroidal anti-inflammatory drugs, analgesi …
Diacerein.
Spencer CM, Wilde MI. Spencer CM, et al. Drugs. 1997 Jan;53(1):98-106; discussion 107-8. doi: 10.2165/00003495-199753010-00007. Drugs. 1997. PMID: 9010651 Review.
Rhein, the active metabolite of diacerein, inhibits interleukin-1 activity. Consequently, collagenase production in articular cartilage is reduced. ...The predominant adverse effects of diacerein are diarrhoea and related disorders....
Rhein, the active metabolite of diacerein, inhibits interleukin-1 activity. Consequently, collagenase production in articular cartila …
Diacerein for osteoarthritis.
Fidelix TS, Macedo CR, Maxwell LJ, Fernandes Moça Trevisani V. Fidelix TS, et al. Cochrane Database Syst Rev. 2014 Feb 10;2014(2):CD005117. doi: 10.1002/14651858.CD005117.pub3. Cochrane Database Syst Rev. 2014. PMID: 24515444 Free PMC article. Review.
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure-modifying drug for OA. ...With respect to adverse effects of diacerein, diarrhoea was most frequent. Given the recent guidance issued by the EMA recommending s …
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure-modifying drug for OA. ... …
OARSI guidelines for the non-surgical management of knee osteoarthritis.
McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM, Hawker GA, Henrotin Y, Hunter DJ, Kawaguchi H, Kwoh K, Lohmander S, Rannou F, Roos EM, Underwood M. McAlindon TE, et al. Osteoarthritis Cartilage. 2014 Mar;22(3):363-88. doi: 10.1016/j.joca.2014.01.003. Epub 2014 Jan 24. Osteoarthritis Cartilage. 2014. PMID: 24462672 Free article.
Treatments of uncertain appropriateness for specific clinical sub-phenotypes included acupuncture, avocado soybean unsaponfiables, chondroitin, crutches, diacerein, glucosamine, intra-articular hyaluronic acid, opioids (oral and transdermal), rosehip, transcutaneous electr …
Treatments of uncertain appropriateness for specific clinical sub-phenotypes included acupuncture, avocado soybean unsaponfiables, chondroit …
[Diacerein].
Passiu G. Passiu G. Ann Ital Med Int. 1986 Jun;1(2):172-4. Ann Ital Med Int. 1986. PMID: 3079362 Review. Italian. No abstract available.
Therapeutic Potential of Diacerein in Management of Pain.
Patel V, Joharapurkar A, Jain M. Patel V, et al. Curr Drug Res Rev. 2022;14(3):215-224. doi: 10.2174/2589977514666220428124623. Curr Drug Res Rev. 2022. PMID: 36281831 Review.
This review discusses the possible mechanism of diacerein in the management of pain. The potential role of rhein and diacerein in the treatment of neuropathic, inflammatory and nociceptive pain is also reviewed. ...The data highlights the role of diacerein in …
This review discusses the possible mechanism of diacerein in the management of pain. The potential role of rhein and diacerein …
Diacerein: Recent insight into pharmacological activities and molecular pathways.
Almezgagi M, Zhang Y, Hezam K, Shamsan E, Gamah M, Al-Shaebi F, Abbas AB, Shoaib M, Saif B, Han Y, Jia R, Zhang W. Almezgagi M, et al. Biomed Pharmacother. 2020 Nov;131:110594. doi: 10.1016/j.biopha.2020.110594. Epub 2020 Aug 25. Biomed Pharmacother. 2020. PMID: 32858499 Free article. Review.
Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) and the active metabolite is rhein. ...This review, the first of its kind, highlights the proposed roles of diacerein in osteoarthritis and discusses recent results supporting its emerging roles …
Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) and the active metabolite is rhein. ...This review, the first …
Is diacerein an alternative for the treatment of osteoarthritis?
Alegría A, Irarrázaval S. Alegría A, et al. Medwave. 2017 Oct 12;17(8):e7041. doi: 10.5867/medwave.2017.08.7041. Medwave. 2017. PMID: 29028791 Review. English, Spanish.
INTRODUCTION: Among the possibilities for the management of osteoarthritis, different pharmacological alternatives have been proposed, being diacerein one of them due to its anti-inflammatory effect. However, diacerein clinical utility is not clear. ...We extracted …
INTRODUCTION: Among the possibilities for the management of osteoarthritis, different pharmacological alternatives have been proposed, being …
340 results