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Prophylactic systemic P2X7 receptor blockade prevents experimental colitis.
Marques CC, Castelo-Branco MT, Pacheco RG, Buongusto F, do Rosário A Jr, Schanaider A, Coutinho-Silva R, de Souza HS. Marques CC, et al. Among authors: buongusto f. Biochim Biophys Acta. 2014 Jan;1842(1):65-78. doi: 10.1016/j.bbadis.2013.10.012. Epub 2013 Oct 30. Biochim Biophys Acta. 2014. PMID: 24184714 Free article.
Macrophage migration inhibitory factor promotes eosinophil accumulation and tissue remodeling in eosinophilic esophagitis.
de Souza HS, Tortori CA, Lintomen L, Figueiredo RT, Bernardazzi C, Leng L, Bucala R, Madi K, Buongusto F, Elia CC, Castelo-Branco MT, Bozza MT. de Souza HS, et al. Among authors: buongusto f. Mucosal Immunol. 2015 Sep;8(5):1154-65. doi: 10.1038/mi.2015.6. Epub 2015 Feb 25. Mucosal Immunol. 2015. PMID: 25712805 Free PMC article. Clinical Trial.
Intraperitoneal but not intravenous cryopreserved mesenchymal stromal cells home to the inflamed colon and ameliorate experimental colitis.
Castelo-Branco MT, Soares ID, Lopes DV, Buongusto F, Martinusso CA, do Rosario A Jr, Souza SA, Gutfilen B, Fonseca LM, Elia C, Madi K, Schanaider A, Rossi MI, Souza HS. Castelo-Branco MT, et al. Among authors: buongusto f. PLoS One. 2012;7(3):e33360. doi: 10.1371/journal.pone.0033360. Epub 2012 Mar 14. PLoS One. 2012. PMID: 22432015 Free PMC article.