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Page 1
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study.
PHOSP-COVID Collaborative Group. PHOSP-COVID Collaborative Group. Lancet Respir Med. 2022 Aug;10(8):761-775. doi: 10.1016/S2213-2600(22)00127-8. Epub 2022 Apr 23. Lancet Respir Med. 2022. PMID: 35472304 Free PMC article.
We found increased inflammatory mediators of tissue damage and repair in both the very severe and the moderate with cognitive impairment clusters compared with the mild cluster, including IL-6 concentration, which was increased in both comparisons (n=626 participants). We found a …
We found increased inflammatory mediators of tissue damage and repair in both the very severe and the moderate with cognitive impairment clu …
Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial.
PD Med Collaborative Group; Gray R, Ives N, Rick C, Patel S, Gray A, Jenkinson C, McIntosh E, Wheatley K, Williams A, Clarke CE. PD Med Collaborative Group, et al. Lancet. 2014 Sep 27;384(9949):1196-205. doi: 10.1016/S0140-6736(14)60683-8. Epub 2014 Jun 11. Lancet. 2014. PMID: 24928805 Clinical Trial.
PDQ-39 mobility scores were 1.4 points (95% CI 0.0-2.9, p=0.05) better in patients allocated MAOBI than in those allocated dopamine agonists. EQ-5D utility scores averaged 0.03 (95% CI 0.01-0.05; p=0.0002) better with levodopa than with levodopa-sparing therapy; rates of d …
PDQ-39 mobility scores were 1.4 points (95% CI 0.0-2.9, p=0.05) better in patients allocated MAOBI than in those allocated dopamine agonists …
GOLDIC therapy in degenerative lumbar spinal stenosis: randomized, controlled trial.
Godek P, Szczepanowska-Wolowiec B, Golicki D. Godek P, et al. Regen Med. 2022 Oct;17(10):709-718. doi: 10.2217/rme-2022-0047. Epub 2022 Jul 28. Regen Med. 2022. PMID: 35899459 Free article. Clinical Trial.
Primary outcomes: Pain intensity in numeric rating scale, Oswestry disability index, Zurich claudication questionnaire, EQ-5D-5L questionnaire. Results: GOLDIC has shown the highest mean differences and number of cases with minimal important difference among groups for eve …
Primary outcomes: Pain intensity in numeric rating scale, Oswestry disability index, Zurich claudication questionnaire, EQ-5D-5L ques …
Comparing patient-reported outcomes across countries: An assessment of methodological challenges.
Sutherland JM, Rajapakshe S, Crump T, Chartrand A, Liu G, Karimuddin A. Sutherland JM, et al. J Health Serv Res Policy. 2021 Jul;26(3):163-171. doi: 10.1177/1355819621990696. Epub 2021 Feb 7. J Health Serv Res Policy. 2021. PMID: 33554667 Free PMC article.
For the English NHS we used published anonymized patient-level data files which include the EQ-5D(3L) patient-reported outcome measure and a number of demographic and clinical characteristics. ...
For the English NHS we used published anonymized patient-level data files which include the EQ-5D(3L) patient-reported outcome measur …
Waiting for surgery: is waiting bad for anyone or everyone?
Sutherland JM, Liu G, Crump RT, Karimuddin AA. Sutherland JM, et al. Hernia. 2017 Dec;21(6):933-940. doi: 10.1007/s10029-017-1684-x. Epub 2017 Oct 20. Hernia. 2017. PMID: 29052082
METHODS: This study was based on a prospectively recruited longitudinal cohort of patients waiting for elective hernia repair surgery. Participants completed the PHQ-9, PEG, EQ-5D(3L) generic instruments, and the condition-specific COMI-hernia. ...
METHODS: This study was based on a prospectively recruited longitudinal cohort of patients waiting for elective hernia repair surgery. Parti …
A cost-utility study of elective haemorrhoidectomies in Canada.
Guo M, Karimuddin AA, Liu G, Crump T, Brown CJ, Raval MJ, Phang PT, Ghuman A, Mok J, Sutherland JM. Guo M, et al. Colorectal Dis. 2024 Mar;26(3):527-533. doi: 10.1111/codi.16867. Epub 2024 Jan 21. Colorectal Dis. 2024. PMID: 38247259
METHODS: Patients undergoing elective haemorrhoidectomies by general and colorectal surgeons in British Columbia, Vancouver, between September 2015 and November 2022, completed preoperatively and postoperatively the EuroQol five-dimension five-level health-related quality of life …
METHODS: Patients undergoing elective haemorrhoidectomies by general and colorectal surgeons in British Columbia, Vancouver, between Septemb …
Incisional hernia repair surgery improves patient reported outcomes.
Manoharan S, Liu G, Crump RT, Karimuddin AA, Scott TM, Sutherland JM. Manoharan S, et al. Am J Surg. 2020 May;219(5):874-878. doi: 10.1016/j.amjsurg.2020.03.027. Epub 2020 Mar 27. Am J Surg. 2020. PMID: 32245611
Study participants self-report their pain, depression and overall quality of life using patient reported outcome measures EQ-5D, PHQ-9 and PEG as they were placed on the waitlist and 6 months after surgery. ...
Study participants self-report their pain, depression and overall quality of life using patient reported outcome measures EQ-5D, PHQ- …
A Cost-Utility Study of Laparoscopic Cholecystectomy for the Treatment of Symptomatic Gallstones.
Sutherland JM, Mok J, Liu G, Karimuddin A, Crump T. Sutherland JM, et al. J Gastrointest Surg. 2020 Jun;24(6):1314-1319. doi: 10.1007/s11605-019-04268-z. Epub 2019 May 29. J Gastrointest Surg. 2020. PMID: 31144191
The objective of this study is to measure health gain, cost and cost utility of elective laparoscopic cholecystectomy. METHODS: Participants completed the EQ-5D(3L) pre-operatively and post-operatively. Quality adjusted life years attributable to cholecystectomy were calcu …
The objective of this study is to measure health gain, cost and cost utility of elective laparoscopic cholecystectomy. METHODS: Participants …
The minimally important difference of the Gastrointestinal Quality of Life Index for symptomatic gallstone surgery.
Sutherland JM, Albanese CM, Crump T, Liu G, Karimuddin A. Sutherland JM, et al. Surg Endosc. 2021 Dec;35(12):6938-6948. doi: 10.1007/s00464-020-08205-z. Epub 2021 Jan 4. Surg Endosc. 2021. PMID: 33398564 Free PMC article.
MATERIALS AND METHODS: The study is based on retrospective analyses of a sample of participants completing the GQLI and the EQ-5D(3L) preoperatively and six months postoperatively in Vancouver, Canada. ...
MATERIALS AND METHODS: The study is based on retrospective analyses of a sample of participants completing the GQLI and the EQ-5D(3L) …
Cost-Utility Study of the Economics of Bunion Correction Surgery.
Sutherland JM, Mok J, Liu G, Crump T, Wing K, Younger A, Penner M, Veljkovic A. Sutherland JM, et al. Foot Ankle Int. 2019 Mar;40(3):336-342. doi: 10.1177/1071100718815663. Epub 2018 Dec 17. Foot Ankle Int. 2019. PMID: 30557044
METHODS: Patients were prospectively recruited from the population of patients seen in a lower-extremity orthopedic clinic and scheduled for isolated bunion surgery. Participants completed EuroQoL's EQ-5D(3L) to measure patients' current general health preoperatively and 6 …
METHODS: Patients were prospectively recruited from the population of patients seen in a lower-extremity orthopedic clinic and scheduled for …
40 results