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Results: 9

1.

Discovery of a pharmacologically active antagonist of the two-pore-domain potassium channel K2P9.1 (TASK-3).

Coburn CA, Luo Y, Cui M, Wang J, Soll R, Dong J, Hu B, Lyon MA, Santarelli VP, Kraus RL, Gregan Y, Wang Y, Fox SV, Binns J, Doran SM, Reiss DR, Tannenbaum PL, Gotter AL, Meinke PT, Renger JJ.

ChemMedChem. 2012 Jan 2;7(1):123-33. doi: 10.1002/cmdc.201100351. Epub 2011 Sep 14.

PMID:
21916012
[PubMed - indexed for MEDLINE]
2.

TASK-3 as a potential antidepressant target.

Gotter AL, Santarelli VP, Doran SM, Tannenbaum PL, Kraus RL, Rosahl TW, Meziane H, Montial M, Reiss DR, Wessner K, McCampbell A, Stevens J, Brunner JI, Fox SV, Uebele VN, Bayliss DA, Winrow CJ, Renger JJ.

Brain Res. 2011 Oct 6;1416:69-79. doi: 10.1016/j.brainres.2011.08.021. Epub 2011 Aug 16.

PMID:
21885038
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore.

Streit AK, Netter MF, Kempf F, Walecki M, Rinné S, Bollepalli MK, Preisig-Müller R, Renigunta V, Daut J, Baukrowitz T, Sansom MS, Stansfeld PJ, Decher N.

J Biol Chem. 2011 Apr 22;286(16):13977-84. doi: 10.1074/jbc.M111.227884. Epub 2011 Mar 1.

PMID:
21362619
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Research into the therapeutic roles of two-pore-domain potassium channels.

Es-Salah-Lamoureux Z, Steele DF, Fedida D.

Trends Pharmacol Sci. 2010 Dec;31(12):587-95. doi: 10.1016/j.tips.2010.09.001. Epub 2010 Oct 15. Review.

PMID:
20951446
[PubMed - indexed for MEDLINE]
5.

Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact.

Bayliss DA, Barrett PQ.

Trends Pharmacol Sci. 2008 Nov;29(11):566-75. doi: 10.1016/j.tips.2008.07.013. Epub 2008 Sep 25. Review.

PMID:
18823665
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis.

Heitzmann D, Derand R, Jungbauer S, Bandulik S, Sterner C, Schweda F, El Wakil A, Lalli E, Guy N, Mengual R, Reichold M, Tegtmeier I, Bendahhou S, Gomez-Sanchez CE, Aller MI, Wisden W, Weber A, Lesage F, Warth R, Barhanin J.

EMBO J. 2008 Jan 9;27(1):179-87. Epub 2007 Nov 22.

PMID:
18034154
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Thiourea-catalyzed enantioselective cyanosilylation of ketones.

Fuerst DE, Jacobsen EN.

J Am Chem Soc. 2005 Jun 29;127(25):8964-5.

PMID:
15969569
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Automated flow-through synthesis of heterocyclic thioethers.

Jönsson D, Warrington BH, Ladlow M.

J Comb Chem. 2004 Jul-Aug;6(4):584-95.

PMID:
15244420
[PubMed]
9.

Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function.

Pei L, Wiser O, Slavin A, Mu D, Powers S, Jan LY, Hoey T.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7803-7. Epub 2003 Jun 2.

PMID:
12782791
[PubMed - indexed for MEDLINE]
Free PMC Article

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