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Results: 1 to 20 of 229

1.

Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients.

Komiyama T, Yajima T, Kubota R, Iwao Y, Sakuraba A, Funakoshi S, Negishi K, Minami I, Tanaka Y, Mae H, Hibi T.

J Crohns Colitis. 2008 Dec;2(4):315-21. doi: 10.1016/j.crohns.2008.05.002. Epub 2008 Jul 3. No abstract available.

PMID:
21172230
[PubMed]
Free Article
2.

Thiopurine S-methyltransferase (TPMT) assessment prior to starting thiopurine drug treatment; a pharmacogenomic test whose time has come.

Ford LT, Berg JD.

J Clin Pathol. 2010 Apr;63(4):288-95. doi: 10.1136/jcp.2009.069252. Review.

PMID:
20354201
[PubMed - indexed for MEDLINE]
3.

Adverse reactions to azathioprine.

Ford L, Berg J.

Intern Med J. 2009 Dec;39(12):859-60; author reply 860-1. doi: 10.1111/j.1445-5994.2009.02073.x. No abstract available.

PMID:
20233255
[PubMed - indexed for MEDLINE]
4.

On therapeutic drug monitoring of thiopurines in inflammatory bowel disease; pharmacology, pharmacogenomics, drug intolerance and clinical relevance.

Van Asseldonk DP, de Boer NK, Peters GJ, Veldkamp AI, Mulder CJ, Van Bodegraven AA.

Curr Drug Metab. 2009 Nov;10(9):981-97. Review.

PMID:
20214590
[PubMed - indexed for MEDLINE]
5.

Pharmacogenetics of thiopurines in inflammatory bowel disease.

Derijks LJ, Wong DR.

Curr Pharm Des. 2010;16(2):145-54. Review.

PMID:
20205660
[PubMed - indexed for MEDLINE]
6.

Thiopurine S-methyltransferase genotype and the use of thiopurines in paediatric inflammatory bowel disease Greek patients.

Gazouli M, Pachoula I, Panayotou I, Mantzaris G, Syriopoulou VP, Goutas N, Vlachodimitropoulos D, Anagnou NP, Roma-Giannikou E.

J Clin Pharm Ther. 2010 Feb;35(1):93-7. doi: 10.1111/j.1365-2710.2009.01041.x.

PMID:
20175817
[PubMed - indexed for MEDLINE]
7.

Thiopurine S-methyltransferase (TPMT) genetic polymorphisms in Mexican newborns.

González-Del Angel A, Bermúdez-López C, Alcántara-Ortigoza MA, Vela-Amieva M, Castillo-Cruz RA, Martínez V, Torres-Espíndola L.

J Clin Pharm Ther. 2009 Dec;34(6):703-8. doi: 10.1111/j.1365-2710.2009.01058.x.

PMID:
20175804
[PubMed - indexed for MEDLINE]
8.

Thiopurines: factors influencing toxicity and response.

Fotoohi AK, Coulthard SA, Albertioni F.

Biochem Pharmacol. 2010 May 1;79(9):1211-20. doi: 10.1016/j.bcp.2010.01.006. Epub 2010 Jan 21.

PMID:
20096268
[PubMed - indexed for MEDLINE]
9.

TPMT and DPD polymorphisms: Efficient screening method for Indian patients considering taking Thiopurine and 5-FU drugs.

Ashavaid TF, Raghavan R, Shah S, Kapadia A, Almel S, Desai D.

Dis Markers. 2009;27(5):231-8. doi: 10.3233/DMA-2009-0668.

PMID:
20037211
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Correlation of genotypes for thiopurine methyltransferase and inosine triphosphate pyrophosphatase with long-term clinical outcomes in Korean patients with inflammatory bowel diseases during treatment with thiopurine drugs.

Jung YS, Cheon JH, Park JJ, Moon CM, Kim ES, Lee JH, Kim SW, Kim JH, Hong SP, Kim TI, Kim WH.

J Hum Genet. 2010 Feb;55(2):121-3. doi: 10.1038/jhg.2009.125. Epub 2009 Dec 4.

PMID:
19960028
[PubMed - indexed for MEDLINE]
11.

Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: differences in enzyme activity.

Serpe L, Calvo PL, Muntoni E, D'Antico S, Giaccone M, Avagnina A, Baldi M, Barbera C, Curti F, Pera A, Eandi M, Zara GP, Canaparo R.

Pharmacogenomics. 2009 Nov;10(11):1753-65. doi: 10.2217/pgs.09.103.

PMID:
19891552
[PubMed - indexed for MEDLINE]
12.

Drug monitoring in inflammatory bowel disease: helpful or dispensable?

Bruns T, Stallmach A.

Dig Dis. 2009;27(3):394-403. doi: 10.1159/000228580. Epub 2009 Sep 24. Review.

PMID:
19786771
[PubMed - indexed for MEDLINE]
13.

Adverse reactions to azathioprine cannot be predicted by thiopurine S-methyltransferase genotype in Japanese patients with inflammatory bowel disease.

Takatsu N, Matsui T, Murakami Y, Ishihara H, Hisabe T, Nagahama T, Maki S, Beppu T, Takaki Y, Hirai F, Yao K.

J Gastroenterol Hepatol. 2009 Jul;24(7):1258-64. doi: 10.1111/j.1440-1746.2009.05917.x.

PMID:
19682195
[PubMed - indexed for MEDLINE]
14.

Application of SNaPshot for analysis of thiopurine methyltransferase gene polymorphism.

Kapoor G, Maitra A; Somlata, Brahmachari V.

Indian J Med Res. 2009 May;129(5):500-5.

PMID:
19675376
[PubMed - indexed for MEDLINE]
15.

TPMT gene polymorphisms: on the doorstep of personalized medicine.

Pavlovic S.

Indian J Med Res. 2009 May;129(5):478-80. No abstract available.

PMID:
19675373
[PubMed - indexed for MEDLINE]
16.

An audit of thiopurine methyltransferase genotyping and phenotyping before intended azathioprine treatment for dermatological conditions.

Vestergaard T, Bygum A.

Clin Exp Dermatol. 2010 Mar;35(2):140-4. doi: 10.1111/j.1365-2230.2009.03446.x. Epub 2009 Jul 29.

PMID:
19663853
[PubMed - indexed for MEDLINE]
17.

Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.

Karas-Kuzelicki N, Mlinaric-Rascan I.

Pharmacogenomics. 2009 Aug;10(8):1309-22. doi: 10.2217/pgs.09.78. Review.

PMID:
19663675
[PubMed - indexed for MEDLINE]
18.

Prospective study of the effects of concomitant medications on thiopurine metabolism in inflammatory bowel disease.

Daperno M, Sostegni R, Canaparo R, Serpe L, Lavagna A, Crocellà L, Castagno F, Vernetto A, Rigazio C, Ercole E, D'Antico S, Pera A, Zara G, Rocca R.

Aliment Pharmacol Ther. 2009 Oct 15;30(8):843-53. doi: 10.1111/j.1365-2036.2009.04106.x. Epub 2009 Jul 24.

PMID:
19650826
[PubMed - indexed for MEDLINE]
19.

Thiopurine therapy is associated with postoperative intra-abdominal septic complications in abdominal surgery for Crohn's disease.

Myrelid P, Olaison G, Sjödahl R, Nyström PO, Almer S, Andersson P.

Dis Colon Rectum. 2009 Aug;52(8):1387-94. doi: 10.1007/DCR.0b013e3181a7ba96.

PMID:
19617749
[PubMed - indexed for MEDLINE]
20.

Thiopurine methyltransferase and thiopurine metabolite testing in patients with inflammatory bowel disease who are taking thiopurine drugs.

Sheffield LJ, Irving P, Gupta A, Byron K, Macrae FA, Phillimore H, Dronavalli M, Rose R, George P, Walmsley T, Dixon B, Poole S, Dooley M, Sparrow M.

Pharmacogenomics. 2009 Jul;10(7):1091-9. doi: 10.2217/pgs.09.60.

PMID:
19604082
[PubMed - indexed for MEDLINE]
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