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Results: 1 to 20 of 21

1.

Synthesis, fluorine-18 radiolabeling, and biological evaluation of N-((E)-4-fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-halophenyl)nortropanes: candidate radioligands for in vivo imaging of the brain dopamine transporter with positron emission tomography.

Stehouwer JS, Daniel LM, Chen P, Voll RJ, Williams L, Plott SJ, Votaw JR, Owens MJ, Howell L, Goodman MM.

J Med Chem. 2010 Aug 12;53(15):5549-57. doi: 10.1021/jm100269c.

PMID:
20597489
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Using positron emission tomography to facilitate CNS drug development.

Lee CM, Farde L.

Trends Pharmacol Sci. 2006 Jun;27(6):310-6. Epub 2006 May 6. Review.

PMID:
16678917
[PubMed - indexed for MEDLINE]
3.

Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder.

Mazei-Robison MS, Couch RS, Shelton RC, Stein MA, Blakely RD.

Neuropharmacology. 2005 Nov;49(6):724-36. Epub 2005 Sep 19.

PMID:
16171832
[PubMed - indexed for MEDLINE]
4.

Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents.

Waterhouse RN.

Mol Imaging Biol. 2003 Nov-Dec;5(6):376-89. Review.

PMID:
14667492
[PubMed - indexed for MEDLINE]
5.

Molecular pathways of neurodegeneration in Parkinson's disease.

Dawson TM, Dawson VL.

Science. 2003 Oct 31;302(5646):819-22. Review.

PMID:
14593166
[PubMed - indexed for MEDLINE]
6.

Plasma membrane monoamine transporters: structure, regulation and function.

Torres GE, Gainetdinov RR, Caron MG.

Nat Rev Neurosci. 2003 Jan;4(1):13-25. Review. No abstract available.

PMID:
12511858
[PubMed - indexed for MEDLINE]
7.

The role of in vivo molecular imaging with PET and SPECT in the elucidation of psychiatric drug action and new drug development.

Talbot PS, Laruelle M.

Eur Neuropsychopharmacol. 2002 Dec;12(6):503-11. Review.

PMID:
12468013
[PubMed - indexed for MEDLINE]
8.

Positron emission tomography: imaging and quantification of neurotransporter availability.

Laruelle M, Slifstein M, Huang Y.

Methods. 2002 Jul;27(3):287-99. Review.

PMID:
12183117
[PubMed - indexed for MEDLINE]
9.

Measurement of dopamine transporter occupancy for multiple injections of cocaine using a single injection of [F-18]FECNT.

Votaw JR, Howell LL, Martarello L, Hoffman JM, Kilts CD, Lindsey KP, Goodman MM.

Synapse. 2002 Jun 15;44(4):203-10.

PMID:
11984856
[PubMed - indexed for MEDLINE]
10.

The role of neuronal and extraneuronal plasma membrane transporters in the inactivation of peripheral catecholamines.

Eisenhofer G.

Pharmacol Ther. 2001 Jul;91(1):35-62. Review.

PMID:
11707293
[PubMed - indexed for MEDLINE]
11.

An admonition when measuring the lipophilicity of radiotracers using counting techniques.

Wilson AA, Jin L, Garcia A, DaSilva JN, Houle S.

Appl Radiat Isot. 2001 Feb;54(2):203-8.

PMID:
11200881
[PubMed - indexed for MEDLINE]
12.

Immunocytochemical localization of the dopamine transporter in human brain.

Ciliax BJ, Drash GW, Staley JK, Haber S, Mobley CJ, Miller GW, Mufson EJ, Mash DC, Levey AI.

J Comp Neurol. 1999 Jun 21;409(1):38-56.

PMID:
10363710
[PubMed - indexed for MEDLINE]
13.

Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites.

Owens MJ, Morgan WN, Plott SJ, Nemeroff CB.

J Pharmacol Exp Ther. 1997 Dec;283(3):1305-22.

PMID:
9400006
[PubMed - indexed for MEDLINE]
Free Article
14.

The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons.

Nirenberg MJ, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM.

J Neurosci. 1996 Jan 15;16(2):436-47.

PMID:
8551328
[PubMed - indexed for MEDLINE]
Free Article
15.

Relationship between lipophilicity and brain extraction of C-11-labeled radiopharmaceuticals.

Dishino DD, Welch MJ, Kilbourn MR, Raichle ME.

J Nucl Med. 1983 Nov;24(11):1030-8.

PMID:
6605416
[PubMed - indexed for MEDLINE]
Free Article
16.

Cocaine receptors on dopamine transporters are related to self-administration of cocaine.

Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ.

Science. 1987 Sep 4;237(4819):1219-23.

PMID:
2820058
[PubMed - indexed for MEDLINE]
17.

Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.

Scheffel U, Boja JW, Kuhar MJ.

Synapse. 1989;4(4):390-2. No abstract available.

PMID:
2603151
[PubMed - indexed for MEDLINE]
18.

The dopamine transporter is absent in parkinsonian putamen and reduced in the caudate nucleus.

Niznik HB, Fogel EF, Fassos FF, Seeman P.

J Neurochem. 1991 Jan;56(1):192-8.

PMID:
1987318
[PubMed - indexed for MEDLINE]
19.

Abnormal dopamine uptake sites in postmortem striatum from patients with Tourette's syndrome.

Singer HS, Hahn IH, Moran TH.

Ann Neurol. 1991 Oct;30(4):558-62.

PMID:
1838678
[PubMed - indexed for MEDLINE]
20.
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