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Results: 10

PubMed Links for Books (Select 2358220)

1.

A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution.

Auld DS, Zhang YQ, Southall NT, Rai G, Landsman M, MacLure J, Langevin D, Thomas CJ, Austin CP, Inglese J.

J Med Chem. 2009 Mar 12;52(5):1450-8. doi: 10.1021/jm8014525.

2.

Compound Management for Quantitative High-Throughput Screening.

Yasgar A, Shinn P, Jadhav A, Auld D, Michael S, Zheng W, Austin CP, Inglese J, Simeonov A.

JALA Charlottesv Va. 2008 Apr;13(2):79-89.

3.

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL, Cantley LC.

Nature. 2008 Mar 13;452(7184):230-3. doi: 10.1038/nature06734.

PMID:
18337823
4.

Pyruvate kinase M2 is a phosphotyrosine-binding protein.

Christofk HR, Vander Heiden MG, Wu N, Asara JM, Cantley LC.

Nature. 2008 Mar 13;452(7184):181-6. doi: 10.1038/nature06667.

PMID:
18337815
5.

Bioluminescent assays for high-throughput screening.

Fan F, Wood KV.

Assay Drug Dev Technol. 2007 Feb;5(1):127-36. Review.

PMID:
17355205
6.

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. Epub 2006 Jul 24.

7.

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.

Dombrauckas JD, Santarsiero BD, Mesecar AD.

Biochemistry. 2005 Jul 12;44(27):9417-29.

PMID:
15996096
8.

Identification of kinase inhibitors by an ATP depletion method.

Singh P, Harden BJ, Lillywhite BJ, Broad PM.

Assay Drug Dev Technol. 2004 Apr;2(2):161-9.

PMID:
15165512
9.

On the origin of cancer cells.

WARBURG O.

Science. 1956 Feb 24;123(3191):309-14. No abstract available.

PMID:
13298683
10.

The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis.

Hannaert V, Yernaux C, Rigden DJ, Fothergill-Gilmore LA, Opperdoes FR, Michels PA.

FEBS Lett. 2002 Mar 13;514(2-3):255-9.

PMID:
11943161
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