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Items: 1 to 20 of 79

1.

Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors.

Yenari MA, Dumas TC, Sapolsky RM, Steinberg GK.

Neurol Res. 2001 Jul;23(5):543-52. Review.

PMID:
11474812
2.

Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors.

Yenari MA, Dumas TC, Sapolsky RM, Steinberg GK.

Ann N Y Acad Sci. 2001 Jun;939:340-57. Review.

PMID:
11462790
3.

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.

Cummings CJ, Sun Y, Opal P, Antalffy B, Mestril R, Orr HT, Dillmann WH, Zoghbi HY.

Hum Mol Genet. 2001 Jul 1;10(14):1511-8.

4.

Protein aggregation after focal brain ischemia and reperfusion.

Hu BR, Janelidze S, Ginsberg MD, Busto R, Perez-Pinzon M, Sick TJ, Siesjö BK, Liu CL.

J Cereb Blood Flow Metab. 2001 Jul;21(7):865-75.

5.

Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions.

Lee JE, Yenari MA, Sun GH, Xu L, Emond MR, Cheng D, Steinberg GK, Giffard RG.

Exp Neurol. 2001 Jul;170(1):129-39.

PMID:
11421590
6.

Calbindin d28k overexpression protects striatal neurons from transient focal cerebral ischemia.

Yenari MA, Minami M, Sun GH, Meier TJ, Kunis DM, McLaughlin JR, Ho DY, Sapolsky RM, Steinberg GK.

Stroke. 2001 Apr;32(4):1028-35.

7.

Stress management - heat shock protein-70 and the regulation of apoptosis.

Beere HM, Green DR.

Trends Cell Biol. 2001 Jan;11(1):6-10. Review.

PMID:
11146277
8.

Negative regulation of the Apaf-1 apoptosome by Hsp70.

Saleh A, Srinivasula SM, Balkir L, Robbins PD, Alnemri ES.

Nat Cell Biol. 2000 Aug;2(8):476-83.

PMID:
10934467
9.

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome.

Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR.

Nat Cell Biol. 2000 Aug;2(8):469-75.

PMID:
10934466
10.

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.

Muchowski PJ, Schaffar G, Sittler A, Wanker EE, Hayer-Hartl MK, Hartl FU.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7841-6.

11.

Heat shock protein 70 inhibits caspase-dependent and -independent apoptosis in Jurkat T cells.

Creagh EM, Carmody RJ, Cotter TG.

Exp Cell Res. 2000 May 25;257(1):58-66.

PMID:
10854054
12.

Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction.

Rajdev S, Hara K, Kokubo Y, Mestril R, Dillmann W, Weinstein PR, Sharp FR.

Ann Neurol. 2000 Jun;47(6):782-91.

PMID:
10852544
13.

The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain.

Heneka MT, Sharp A, Klockgether T, Gavrilyuk V, Feinstein DL.

J Cereb Blood Flow Metab. 2000 May;20(5):800-11.

14.

Protein aggregation after transient cerebral ischemia.

Hu BR, Martone ME, Jones YZ, Liu CL.

J Neurosci. 2000 May 1;20(9):3191-9.

15.

Benign focal ischemic preconditioning induces neuronal Hsp70 and prolonged astrogliosis with expression of Hsp27.

Currie RW, Ellison JA, White RF, Feuerstein GZ, Wang X, Barone FC.

Brain Res. 2000 Apr 28;863(1-2):169-81.

PMID:
10773205
16.

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity.

Neckers L, Schulte TW, Mimnaugh E.

Invest New Drugs. 1999;17(4):361-73. Review.

PMID:
10759403
17.
18.

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease.

Chai Y, Koppenhafer SL, Bonini NM, Paulson HL.

J Neurosci. 1999 Dec 1;19(23):10338-47.

19.

The neuroprotective potential of heat shock protein 70 (HSP70).

Yenari MA, Giffard RG, Sapolsky RM, Steinberg GK.

Mol Med Today. 1999 Dec;5(12):525-31. Review.

PMID:
10562718
20.
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