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Hepatogastroenterology. 1998 Nov-Dec;45(24):1944-9.

Liver transplantation for hepatocellular carcinoma?

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  • 1Liver Transplant Program, Loyola University at Chicago, Maywood, IL 60153, USA.


The worldwide experience of the largest transplant programs with hepatic resection and liver transplantation for primary hepatic cancer are reviewed. The pros and cons for resection as well as for transplantation are presented. The choice between resection or transplantation may depend upon the geographic location of the individual patient, their financial resources, the availability of specific surgical expertise, as well as a panoply of medical/surgical factors that define what can or cannot be accomplished. In the absence of limiting factors, transplantation appears to be the surgical method of choice for small neoplastic lesions less than 5 cm in diameter, particularly when the number of lesions is small (< or = 3) and the cancer occurs in the setting of cirrhosis. Surgical resection is the preferred procedure for larger lesions and for those occurring in individuals without confounding cirrhosis.

[PubMed - indexed for MEDLINE]
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