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J Head Trauma Rehabil. 1999 Feb;14(1):9-21.

Epidemiology and pathogenesis of posttraumatic headache.

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  • 1Headache Management and Neurology, University of West Florida, Department of Psychology, Pensacola, Florida 32503, USA.


This article presents an overview of the epidemiology and pathophysiology of posttraumatic headache. It reviews definitions of mild head injury (MHI), mild traumatic brain injury (MTBI), and concussion, and discusses the confusion that often occurs with these terms. Headache types and their pathophysiology are examined in detail. Just as the exact pathophysiology is unknown for migraine and other types of headache, the exact pathophysiology of headache after trauma is also still unknown in many cases. Possible connections between head or neck injuries and headache are reviewed, as well as hypothesized neurochemical changes that may occur in both migraine and traumatic brain injury (TBI). Psychological and legal factors are also considered.

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