Send to:

Choose Destination
See comment in PubMed Commons below
Clin Chest Med. 1998 Dec;19(4):777-91, ix.

Pulmonary manifestations of Goodpasture's syndrome. Antiglomerular basement membrane disease and related disorders.

Author information

  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, USA.


Goodpasture's syndrome, or antiglomerular basement membrane disease, is a disorder in which lungs and kidneys are affected by the binding of anti-GBM antibodies, leading to pulmonary hemorrhage and glomerulonephritis with rapidly progressive renal insufficiency. Recent advances in the understanding of disease pathogenesis and diagnosis and treatment have significantly improved our ability to recognize the syndrome, distinguish it from other similar disorders, and offer successful treatment. This article focuses on the pathogenetic features, clinical manifestations, diagnostic strategies, and therapeutic principles of anti-GBM disease.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk