-
Azithromycin compared with minocycline in the treatment of acne comedonica and papulo-pustulosa.
Department of Dermatology, Clinical Hospital Center, Rijeka, Croatia.
This open study was conducted in 72 outpatients with acne vulgaris, to compare the clinical efficacy and tolerability of azithromycin and minocycline. Azithromycin was administered as a single oral dose (500 mg/day) for 4 days in four cycles every 10 days and minocycline was administered 100 mg daily for 6 weeks. Improvement was assessed 6 weeks after initiation of treatment with a four-graded scale. A satisfactory clinical response was observed in 75.8% of the patients treated with azithromycin and in 70.5% of those treated with minocycline. There were no significant differences between these two acne treatments in terms of reduction of the number of lesions (p> 0.05). Both agents were well tolerated and mild side effects were reported in 10.3% of azithromycin and 11.7% of minocycline treated patients. We conclude that azithromycin is at least as clinically effective and well tolerated as minocycline as treatment of facial comedonic and papulopustular acne.
PMID: 9876055 [PubMed - indexed for MEDLINE]
-
Patient Drug Information
-
Erythromycin (ERY-C® , Ery-Tab® , Erythromycin Base Filmtab® , ...)
Erythromycin is an antibiotic used to treat certain infections caused by bacteria, such as bronchitis; diphtheria; Legionnaires' disease; pertussis (whooping cough); pneumonia; rheumatic fever; venereal disease (VD); and...
-
Azithromycin (Zithromax® , Zithromax® Single Dose Packets, Zithromax® Tri-Paks® , ...)
Azithromycin is used to treat certain infections caused by bacteria, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, skin, and throat. Azithromycin is in a class of ...
-
Minocycline Oral (Dynacin® , Minocin® , Myrac® )
Minocycline is used to treat bacterial infections including pneumonia and other respiratory tract infections; acne; and infections of skin, genital, and urinary systems. It can also be used to eliminate bacteria from you...