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Bioorg Med Chem Lett. 1998 Sep 8;8(17):2285-90.

In vitro selection of phosphorothiolated aptamers.

Author information

  • 1Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA.

Abstract

A pool of RNA molecules that contained exclusively phosphorothioate internucleoside linkages was used as a starting point for the selection of aptamers that bind to basic fibroblast growth factor (bFGF), and appear to act as heparin mimics.

PMID:
9873529
[PubMed - indexed for MEDLINE]
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