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Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15508-12.

Targeted expression of teashirt induces ectopic eyes in Drosophila.

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  • 1Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720-3200, USA.

Abstract

teashirt was initially identified as a gene required for the specification of the trunk segments in Drosophila embryogenesis and encodes a transcription factor with zinc finger motifs. We report here that targeted expression of teashirt in imaginal discs is sufficient to induce ectopic eye formation in non-eye tissues, a phenotype similar to that produced from targeted expression of eyeless, dachshund, and eyes absent. Furthermore, teashirt and eyeless induce the expression of each other, suggesting that teashirt is part of the gene network that functions to specify eye identity.

PMID:
9860999
[PubMed - indexed for MEDLINE]
PMCID:
PMC28073
Free PMC Article
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