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Genome Res. 1998 Nov;8(11):1097-108.

Toward a complete human genome sequence.

Author information

  • 1Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK;
  • 2Washington University School of Medicine, St. Louis, Missouri 63108 USA

Abstract

We have begun a joint program as part of a coordinated international effort to determine a complete human genome sequence. Our strategy is to map large-insert bacterial clones and to sequence each clone by a random shotgun approach followed by directed finishing. As of September 1998, we have identified the map positions of bacterial clones covering approximately 860 Mb for sequencing and completed >98 Mb ( approximately 3.3%) of the human genome sequence. Our progress and sequencing data can be accessed via the World Wide Web (http://webace.sanger.ac.uk/HGP/ or http://genome.wustl.edu/gsc/).

PMID:
9847074
[PubMed - indexed for MEDLINE]
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