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1: Nat Struct Biol. 1998 Dec;5(12):1029-32.Click here to read Links
Comment in:
Nat Struct Biol. 1998 Dec;5(12):1019-20.

100,000 protein structures for the biologist.

Sali A.

Laboratories of Molecular Biophysics, The Rockefeller University, New York, New York 10021, USA. sali@rockefeller.edu

Structural genomics promises to deliver experimentally determined three-dimensional structures for many thousands of protein domains. These domains will be carefully selected, so that the methods of fold assignment and comparative protein structure modeling will result in useful models for most other protein sequences. The impact on biology will be dramatic.

PMID: 9846869 [PubMed - indexed for MEDLINE]