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C R Acad Sci III. 1998 Oct;321(10):857-63.

Endogenous retroviruses and multiple sclerosis. II. HERV-7q.

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  • 1Inserm, Paris, France.

Abstract

The search for new endogenous retroviral sequences, on the basis of sequence homologies with the pol gene of the recently reported multiple sclerosis associated retrovirus (MSRV), allowed us to identify a full length endogenous retrovirus sequence located on the long arm of human chromosome 7. This retrovirus, HERV-7q, includes in its env region, within a single 1,620 bp open reading frame, a 664 bp domain almost identical to a 3' non-coding region of the rab7 gene. Transcripts encompassing both the env and the 3' LTR regions of HERV-7q have already been identified as expressed sequence tags, suggesting that this env-like gene might code for a 538 amino acid long deduced protein.

PMID:
9835022
[PubMed - indexed for MEDLINE]
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