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    Am Fam Physician. 1998 Nov 1;58(7):1627-34, 1641-2.

    Carvedilol: the new role of beta blockers in congestive heart failure.

    Vanderhoff BT, Ruppel HM, Amsterdam PB.

    Grant Medical Center, Columbus, Ohio, USA.

    The prognosis remains poor for patients with congestive heart failure (CHF), despite reduced mortality rates resulting from the addition of angiotensin converting enzyme inhibitors to traditional treatment regimens. Because much of the myocardial damage that occurs in patients with CHF may be related to sympathetic activation, interest in the use of beta blockers has grown. Recent studies have shown the benefits of beta blocker therapy in many patients with heart failure. Carvedilol, the first beta blocker labeled in the United States specifically for the treatment of heart failure, has been shown to improve left ventricular ejection fraction and may reduce mortality.

    PMID: 9824960 [PubMed - indexed for MEDLINE]

    Supplemental Content

    Patient drug information

    • Carvedilol (Coreg®, Coreg CR®)

      Carvedilol is used to treat heart failure (condition in which the heart cannot pump enough blood to all parts of the body) and high blood pressure. It also is used to treat people whose hearts cannot pump blood well as a...